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Ways of Coping and Biomarkers of an Increased Atherothrombotic Cardiovascular Disease Risk in Elderly Individuals
المؤلفون المشاركون
von Känel, Roland
Mills, Paul J.
Ziegler, Michael G.
Patterson, Thomas L.
Allison, Matthew
Dimsdale, Joel E.
Ancoli-Israel, Sonia
Grant, Igor
Roepke, Susan K.
Mausbach, Brent T.
المصدر
Cardiovascular Psychiatry and Neurology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-17
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the relationship between coping and atherothrombotic biomarkers of an increased cardiovascular disease (CVD) risk in the elderly.
Methods.
We studied 136 elderly caregiving and noncaregiving men and women who completed the Ways of Coping Checklist to assess problem-focused coping, seeking social support (SSS), blamed self, wishful thinking, and avoidance coping.
They had circulating levels of 12 biomarkers measured.
We also probed for potential mediator and moderator variables (chronic stress, affect, health behavior, autonomic activity) for the relation between coping and biomarkers.
Results.
After controlling for demographic and CVD risk factors, greater use of SSS was associated with elevated levels of serum amyloid A (P=0.001), C-reactive protein (CRP) (P=0.002), vascular cellular adhesion molecule (VCAM)-1 (P=0.021), and D-dimer (P=0.032).
There were several moderator effects.
For instance, greater use of SSS was associated with elevated VCAM-1 (P<0.001) and CRP (P=0.001) levels in subjects with low levels of perceived social support and positive affect, respectively.
The other coping styles were not significantly associated with any biomarker.
Conclusions.
Greater use of SSS might compromise cardiovascular health through atherothrombotic mechanisms, including elevated inflammation (i.e., serum amyloid A, CRP, VCAM-1) and coagulation (i.e., D-dimer) activity.
Moderating variables need to be considered in this relationship.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
von Känel, Roland& Mausbach, Brent T.& Dimsdale, Joel E.& Mills, Paul J.& Patterson, Thomas L.& Ancoli-Israel, Sonia…[et al.]. 2012. Ways of Coping and Biomarkers of an Increased Atherothrombotic Cardiovascular Disease Risk in Elderly Individuals. Cardiovascular Psychiatry and Neurology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-505426
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
von Känel, Roland…[et al.]. Ways of Coping and Biomarkers of an Increased Atherothrombotic Cardiovascular Disease Risk in Elderly Individuals. Cardiovascular Psychiatry and Neurology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-505426
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
von Känel, Roland& Mausbach, Brent T.& Dimsdale, Joel E.& Mills, Paul J.& Patterson, Thomas L.& Ancoli-Israel, Sonia…[et al.]. Ways of Coping and Biomarkers of an Increased Atherothrombotic Cardiovascular Disease Risk in Elderly Individuals. Cardiovascular Psychiatry and Neurology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-505426
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505426
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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