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Vascular Response to Graded Angiotensin II Infusion in Offspring Subjected to High-Salt Drinking Water during Pregnancy : The Effect of Blood Pressure, Heart Rate, Urine Output, Endothelial Permeability, and Gender
المؤلفون المشاركون
Pezeshki, Zahra
Eshraghi-Jazi, Fatemeh
Nematbakhsh, Mehdi
المصدر
International Journal of Vascular Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-17
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Rennin-angiotensin system and salt diet play important roles in blood pressure control.
We hypothesized that the high-salt intake during pregnancy influences the degree of angiotensin-dependent control of the blood pressure in adult offspring.
Methods.
Female Wistar rats in two groups (A and B) were subjected to drink tap and salt water, respectively, during pregnancy.
The offspring were divided into four groups as male and female offspring from group A (groups 1 and 2) and from group B (groups 3 and 4).
In anesthetized matured offspring mean arterial pressure (MAP), heart rate and urine output were measured in response to angiotensin II (AngII) (0-1000 ng/kg/min, iv) infusion.
Results.
An increase in MAP was detected in mothers with salt drinking water (P<0.05).
The body weight increased and kidney weight decreased significantly in male offspring from group 3 in comparison to group 1 (P<0.05).
MAP and urine volume in response to AngII infusion increased in group 3 (P<0.05).
These findings were not observed in female rats.
Conclusion.
Salt overloading during pregnancy had long-term effects on kidney weight and increased sex-dependent response to AngII infusion in offspring (adult) that may reveal the important role of diet during pregnancy in AngII receptors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pezeshki, Zahra& Eshraghi-Jazi, Fatemeh& Nematbakhsh, Mehdi. 2014. Vascular Response to Graded Angiotensin II Infusion in Offspring Subjected to High-Salt Drinking Water during Pregnancy : The Effect of Blood Pressure, Heart Rate, Urine Output, Endothelial Permeability, and Gender. International Journal of Vascular Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-505505
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pezeshki, Zahra…[et al.]. Vascular Response to Graded Angiotensin II Infusion in Offspring Subjected to High-Salt Drinking Water during Pregnancy : The Effect of Blood Pressure, Heart Rate, Urine Output, Endothelial Permeability, and Gender. International Journal of Vascular Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-505505
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pezeshki, Zahra& Eshraghi-Jazi, Fatemeh& Nematbakhsh, Mehdi. Vascular Response to Graded Angiotensin II Infusion in Offspring Subjected to High-Salt Drinking Water during Pregnancy : The Effect of Blood Pressure, Heart Rate, Urine Output, Endothelial Permeability, and Gender. International Journal of Vascular Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-505505
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505505
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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