Epidemiological and Clinical Features of Hepatitis B Virus Genotypes among Immigrants in Southern Italy
المؤلفون المشاركون
Martinelli, Domenico
Di Tullio, Rocco
Scotto, Gaetano
Fazio, Vincenzina
المصدر
Hepatitis Research and Treatment
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-04-22
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background/aims.
This study aims to determine the distribution and clinical features of HBV-genotypes in a population of immigrants affected by HBV-infection.
Methods.
Between 01/2003 and 03/2009, 1623 immigrants were tested for HBV-infection.
Biochemical and virological activities were determined in HBsAg-positive patients; HBV-genotypes were determined, by the INNO-LiPA HBV Genotyping, in the subjects with HBV DNA detectable.
In every patient we evaluated the stage and classified the infection as inactive carrier, mild or moderate/severe chronic hepatitis, cirrhosis, and/or HCC.
Results.
Among the tested subjects, 191 (11.7%) resulted HBsAg-positive, and in 144/191 (75.4%) serum HBV-DNA was detectable.
The genotype distribution was as follows: 45,13% genotype E, 18,1% genotype D, 15,3% genotype B, 13,2% genotype C, 4,9% genotype A, 3,5% mixed genotypes (A–D).
The evaluation of liver disease degree showed that 24.6% patients were inactive carriers of HBV infection, 19.4% presented a immunotolerance phase, 34.5% had mild chronic hepatitis, 13.6% had a moderate/severe chronic hepatitis, 6.3% had cirrhosis, and 1.6% presented HCC.
Conclusions.
Our study evidences a high prevalence of HBV-infection in immigrants, and the potentiality of migratory flow in the introduction of genotype non-D hepatitis B virus.
The Hepatitis B virus genotypes presented significant differences in epidemiological and clinical characteristics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Scotto, Gaetano& Martinelli, Domenico& Di Tullio, Rocco& Fazio, Vincenzina. 2010. Epidemiological and Clinical Features of Hepatitis B Virus Genotypes among Immigrants in Southern Italy. Hepatitis Research and Treatment،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-505568
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Scotto, Gaetano…[et al.]. Epidemiological and Clinical Features of Hepatitis B Virus Genotypes among Immigrants in Southern Italy. Hepatitis Research and Treatment No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-505568
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Scotto, Gaetano& Martinelli, Domenico& Di Tullio, Rocco& Fazio, Vincenzina. Epidemiological and Clinical Features of Hepatitis B Virus Genotypes among Immigrants in Southern Italy. Hepatitis Research and Treatment. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-505568
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505568
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر