Diversity of Mycobacterium tuberculosis Isolates from New Pulmonary Tuberculosis Cases in Addis Ababa, Ethiopia
المؤلفون المشاركون
Yamuah, Lawrence
Jordan, Annemie M.
Walzl, Gerhard
Bekele, Yonas
Aseffa, Abraham
Mihret, Adane
Howe, Rawleigh
Loxton, Andre G.
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-22
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Understanding the genetic diversity of Mycobacterium tuberculosis is needed for a better understanding of the epidemiology of TB and could have implications for the development of new diagnostics, drugs, and vaccines.
M.
tuberculosis isolates were characterized using spoligotyping and were compared with the SpoIDB4 database of the Pasteur Institute of Guadeloupe.
A total of 53 different patterns were identified among 192 isolates examined.
169 of the isolates were classified into one of the 33 shared SITs, whereas the remaining 23 corresponded to 20 orphan patterns.
54% of the isolates were ascribed to the T family, a family which has not been well defined to date.
Other prominent families were CAS, Haarlem, LAM, Beijing, and Unknown comprising 26%, 13%, 2.6%, 0.5%, and 2.1%, respectively.
Among HIV-positive patients, 10 patterns were observed among 25 isolates.
The T (38.5%), H (26.9%), and CAS (23.1%) families were the most common among HIV-positive individuals.
The diversity of the M.
tuberculosis strains found in this study is very high, and there was no difference in the distribution of families in HIV-positive and HIV-negative TB patients except the H family.
Tuberculosis transmission in Addis Ababa is due to only the modern M.
tuberculosis families (CAS, LAM, T, Beijing, Haarlem, and U).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mihret, Adane& Bekele, Yonas& Loxton, Andre G.& Jordan, Annemie M.& Yamuah, Lawrence& Aseffa, Abraham…[et al.]. 2012. Diversity of Mycobacterium tuberculosis Isolates from New Pulmonary Tuberculosis Cases in Addis Ababa, Ethiopia. Tuberculosis Research and Treatment،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-505901
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mihret, Adane…[et al.]. Diversity of Mycobacterium tuberculosis Isolates from New Pulmonary Tuberculosis Cases in Addis Ababa, Ethiopia. Tuberculosis Research and Treatment No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-505901
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mihret, Adane& Bekele, Yonas& Loxton, Andre G.& Jordan, Annemie M.& Yamuah, Lawrence& Aseffa, Abraham…[et al.]. Diversity of Mycobacterium tuberculosis Isolates from New Pulmonary Tuberculosis Cases in Addis Ababa, Ethiopia. Tuberculosis Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-505901
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505901
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر