Multifactorial Hypercalcemia and Literature Review on Primary Hyperparathyroidism Associated with Lymphoma
المؤلفون المشاركون
Palma Diaz, Miguel Fernando
Yeh, Michael W.
Isorena, Jennifer P.
Korenman, Stanley G.
Maletkovic, Jelena
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-05
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
The most common cause of hypercalcemia in hospitalized patients is malignancy.
Primary hyperparathyroidism most commonly causes hypercalcemia in the outpatient setting.
These two account for over 90% of all cases of hypercalcemia.
Hypercalcemia can be divided into PTH-mediated and PTH-independent variants.
Primary hyperparathyroidism, familial hypocalciuric hypercalcemia, familial hyperparathyroidism, and secondary hyperparathyroidism are PTH mediated.
The most common PTH-independent type of hypercalcemia is malignancy related.
Several mechanisms lead to hypercalcemia in malignancy-direct osteolysis by metastatic disease or, more commonly, production of humoral factors by the primary tumor also known as humoral hypercalcemia of malignancy that accounts for about 80% of malignancy-related hypercalcemia.
The majority of HHM is caused by tumor-produced parathyroid hormone-related protein and less frequently production of 1,25-dihydroxyvitamin D or parathyroid hormone by the tumor.
We report the rare case of a patient with hypercalcemia and diagnosed primary hyperparathyroidism.
The patient had persistent hypercalcemia after surgical removal of parathyroid adenoma with recorded significant decrease in PTH level.
After continued investigation it was found that the patient also had elevated 1,25-dihydroxyvitamin D and further studies confirmed a large spleen mass that was later confirmed to be a lymphoma.
This is a rare example of two concomitant causes of hypercalcemia requiring therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maletkovic, Jelena& Isorena, Jennifer P.& Palma Diaz, Miguel Fernando& Korenman, Stanley G.& Yeh, Michael W.. 2014. Multifactorial Hypercalcemia and Literature Review on Primary Hyperparathyroidism Associated with Lymphoma. Case Reports in Endocrinology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-505991
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maletkovic, Jelena…[et al.]. Multifactorial Hypercalcemia and Literature Review on Primary Hyperparathyroidism Associated with Lymphoma. Case Reports in Endocrinology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-505991
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maletkovic, Jelena& Isorena, Jennifer P.& Palma Diaz, Miguel Fernando& Korenman, Stanley G.& Yeh, Michael W.. Multifactorial Hypercalcemia and Literature Review on Primary Hyperparathyroidism Associated with Lymphoma. Case Reports in Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-505991
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505991
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر