Pistacia atlantica Resin Has a Dose-Dependent Effect on Angiogenesis and Skin Burn Wound Healing in Rat
المؤلفون المشاركون
Sanei, Mohammad Hossein
Javanmard, Shaghayegh Haghjooy
Baradaran Mahdavi, Mohammad Mehdi
Zandifar, Alireza
Zolfaghari, Behzad
Haghdoost, Faraidoon
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives.
The aim of the present study was to evaluate the effect of Pistacia atlantica resin extract on the rat skin burn wound healing.
Methods.
Thirty-two Wistar rats were divided into four groups and treated by vehicle, 5%, 10%, and 20% concentration of Pistacia atlantica resin extract for 14 days (G1, G2, G3, and G4, resp.).
The efficacy of treatment was assessed based on reduction of burn wound size and histological and molecular characteristics.
Results.
α-Pinene (46.57%) was the main content of essential oil of resin.
There were no statistically significant differences between groups according to wound size analysis.
The mean histological wound healing scores were not statistically different.
Capillary counts of G2 and G3 were significantly higher than those of the G1 (P=0.042 and 0.032, resp.).
NO concentration in wound fluids on the 5th day of study was not significantly different between groups (P=0.468).
But bFGF concentration in G2 and G3 and PDGF concentration in G3 were significantly higher in comparison to G1 (P=0.043, 0.017, and 0.019, resp.).
Conclusion.
Our results revealed that Pistacia atlantica resin extract has a concentration-dependent effect on the healing of burn wounds after 14 days of treatment by increasing the concentration of bFGF and PDGF and also through improving the angiogenesis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Haghdoost, Faraidoon& Baradaran Mahdavi, Mohammad Mehdi& Zandifar, Alireza& Sanei, Mohammad Hossein& Zolfaghari, Behzad& Javanmard, Shaghayegh Haghjooy. 2013. Pistacia atlantica Resin Has a Dose-Dependent Effect on Angiogenesis and Skin Burn Wound Healing in Rat. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-506018
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Haghdoost, Faraidoon…[et al.]. Pistacia atlantica Resin Has a Dose-Dependent Effect on Angiogenesis and Skin Burn Wound Healing in Rat. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-506018
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Haghdoost, Faraidoon& Baradaran Mahdavi, Mohammad Mehdi& Zandifar, Alireza& Sanei, Mohammad Hossein& Zolfaghari, Behzad& Javanmard, Shaghayegh Haghjooy. Pistacia atlantica Resin Has a Dose-Dependent Effect on Angiogenesis and Skin Burn Wound Healing in Rat. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-506018
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-506018
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر