Antioxidant Activities of Plumbagin and Its Cu (II)‎ Complex

المؤلفون المشاركون

Tan, Mingxiong
Liang, Hong
Liu, Yancheng
Luo, Xujian
Chen, Zhenfeng

المصدر

Bioinorganic Chemistry and Applications

العدد

المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2011-10-23

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

الأحياء

الملخص EN

Plumbagin and its Cu (II) complex [Cu (plumbagin)2]·H2O have been synthesized, and their antioxidant activities towards the inhibitory effect on DPPH free radical, reducing power, total antioxidant capacity, and inhibition on lipid peroxidation were investigated.

Plumbagin and its Cu (II) complex were found to exhibit scavenging activities on DPPH radical with the inhibitory rate of 41% and 24%, respectively.

The reducing power of plumbagin was outstanding at the concentrations of 1.0, 1.5, and 2.0 mg/mL, compared to Cu (II) complex and synthetic antioxidant 2,6-di-ter-butyl-4-methylphenol (BHT); the highest level reached 1.333 for plumbagin and 0.581 for Cu (II) complex.

Also, the inhibition on lipid peroxidation of plumbagin was higher than that of Cu (II) complex and BHT, 46.4% for plumbagin and 24.5% for Cu (II) complex.

The results give a strong impact for designing anticancer drugs, combined with their potential cytotoxic and antioxidant activities, which can be targeted selectively against cancer cells and increase their therapeutic index and additional advantages over other anticancer drugs.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Tan, Mingxiong& Liu, Yancheng& Luo, Xujian& Chen, Zhenfeng& Liang, Hong. 2011. Antioxidant Activities of Plumbagin and Its Cu (II) Complex. Bioinorganic Chemistry and Applications،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-506500

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Tan, Mingxiong…[et al.]. Antioxidant Activities of Plumbagin and Its Cu (II) Complex. Bioinorganic Chemistry and Applications No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-506500

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Tan, Mingxiong& Liu, Yancheng& Luo, Xujian& Chen, Zhenfeng& Liang, Hong. Antioxidant Activities of Plumbagin and Its Cu (II) Complex. Bioinorganic Chemistry and Applications. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-506500

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-506500