Adduct of Malondialdehyde to Hemoglobin : A New Marker of Oxidative Stress That Is Associated with Significant Morbidity in Preterm Infants
المؤلفون المشاركون
Picaud, Jean-Charles
Steghens, Jean-Paul
Haÿs, Stéphane
Cipierre, Cécile
Maucort-Boulch, Delphine
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
Preterm infants (PT) are particularly exposed to oxidative stress (OS), and a blood-sparing marker, the malondialdehyde adduct to hemoglobin (MDA-Hb), may be useful to accurately assess OS-related neonatal morbidity.
In a prospective study, MDA-Hb concentrations were assessed in two groups of PT, one with and one without severe neonatal morbidity as estimated by a composite index of severe morbidity (ISM).
All PT born in a single tertiary care NICU (<32 weeks and birth weight <1500 g) were consecutively included.
MDA-Hb and blood glutathione (GSH) concentrations were measured by liquid chromatography-mass spectrometry during the first 6 weeks of life.
Linear regressions and a multilevel model were fitted to study the relationship between MDA-Hb or GSH and ISM.
Of the 83 PT (mean ± SD: 28.3±2 weeks, 1089±288 g), 21% presented severe neonatal morbidity.
In the multivariate model, MDA-Hb concentrations were significantly higher in the ISM+ group than in the ISM– group during the first 6 weeks of life (P=0.009).
No significant difference in GSH concentrations was observed between groups (P=0.180).
MDA-Hb is a marker of interest for estimating oxidative stress in PT and could be useful to evaluate the impact of strategies to improve perinatal outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cipierre, Cécile& Haÿs, Stéphane& Maucort-Boulch, Delphine& Steghens, Jean-Paul& Picaud, Jean-Charles. 2013. Adduct of Malondialdehyde to Hemoglobin : A New Marker of Oxidative Stress That Is Associated with Significant Morbidity in Preterm Infants. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-506528
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cipierre, Cécile…[et al.]. Adduct of Malondialdehyde to Hemoglobin : A New Marker of Oxidative Stress That Is Associated with Significant Morbidity in Preterm Infants. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-506528
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cipierre, Cécile& Haÿs, Stéphane& Maucort-Boulch, Delphine& Steghens, Jean-Paul& Picaud, Jean-Charles. Adduct of Malondialdehyde to Hemoglobin : A New Marker of Oxidative Stress That Is Associated with Significant Morbidity in Preterm Infants. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-506528
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-506528
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر