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Expression of CD44v6 and Its Association with Prognosis in Epithelial Ovarian Carcinomas
المؤلفون المشاركون
Zhou, Dang-xia
Xue, Ya-hong
Liu, Yun-xia
المصدر
Pathology Research International
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-23
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The aim of this study was to evaluate CD44v6 protein expression and its prognostic value of CD44v6 in ovarian carcinoma.
The expression of CD44v6 was analyzed in 62 patients with ovarian carcinoma by immunohistochemical method.
The data obtained were analyzed by univariate and multivariate analyses.
The present study clearly demonstrates that tumor tissues from 41 (66.1%) patients showed positive expression with CD44v6.
The expression of CD44v6 was significantly correlated with histological type, FIGO stage and histological grade of ovarian carcinomas.
Concerning the prognosis, the survival period of patients with CD44v6 positive was shorter than that of patients with CD44v6 negative (36.6% versus 66.7%, 5-year survival, P<0.05).
Univariate analysis showed that CD44v6 expression, histological type, FIGO stage and histological grade were associated with 5-year survival, and CD44v6 expression was associated with histological type, FIGO stage and histological grade and 5-year survival.
In multivariate analysis, using the COX-regression model, CD44v6 expression was important prognostic factor.
In conclusion, these results suggest that CD44v6 may be related to histological type, FIGO stage and histological grade of ovarian carcinomas, and CD44v6 may be an important molecular marker for poor prognosis in ovarian carcinomas.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Dang-xia& Liu, Yun-xia& Xue, Ya-hong. 2012. Expression of CD44v6 and Its Association with Prognosis in Epithelial Ovarian Carcinomas. Pathology Research International،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-507206
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Dang-xia…[et al.]. Expression of CD44v6 and Its Association with Prognosis in Epithelial Ovarian Carcinomas. Pathology Research International No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-507206
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Dang-xia& Liu, Yun-xia& Xue, Ya-hong. Expression of CD44v6 and Its Association with Prognosis in Epithelial Ovarian Carcinomas. Pathology Research International. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-507206
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507206
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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