Cytokine Pattern of T Lymphocytes in Acute Schistosomiasis mansoni Patients following Treated Praziquantel Therapy
المؤلفون المشاركون
Soares Silveira, Alda Maria
Fernandes Costa-Silva, Matheus
Cardoso de Oliveira Silveira, Amanda
Alves Oliveira-Fraga, Lúcia
Martins-Filho, Olindo Assis
Silveira-Lemos, Denise
Barbosa Alvarez, Maria Carolina
Teixeira-Carvalho, Andrea
Corrêa-Oliveira, Rodrigo
Gazzinelli, Giovanni
Azevedo Batista, Mauricio
المصدر
Journal of Parasitology Research
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-01-20
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Acute schistosomiasis is associated with a primary exposure and is more commonly seen in nonimmune individuals traveling through endemic regions.
In this study, we have focused on the cytokine profile of T lymphocytes evaluated in circulating leukocytes of acute Schistosomiasis mansoni-infected patients (ACT group) before and after praziquantel treatment (ACT-TR group).
Our data demonstrated increased values of total leukocytes, eosinophils, and monocytes in both groups.
Interestingly, we have observed that patients treated with praziquantel showed increased values of lymphocytes as compared with noninfected group (NI) or ACT groups.
Furthermore, a decrease of neutrophils in ACT-TR was observed when compared to ACT group.
Analyses of short-term in vitro whole blood stimulation demonstrated that, regardless of the presence of soluble Schistosoma mansoni eggs antigen (SEA), increased synthesis of IFN-γ and IL-4 by T-cells was observed in the ACT group.
Analyses of cytokine profile in CD8 T cells demonstrated higher percentage of IFN-γ and IL-4 cells in both ACT and ACT-TR groups apart from increased percentage of IL-10 cells only in the ACT group.
This study is the first one to point out the relevance of CD8 T lymphocytes in the immune response induced during the acute phase of schistosomiasis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Silveira-Lemos, Denise& Fernandes Costa-Silva, Matheus& Cardoso de Oliveira Silveira, Amanda& Azevedo Batista, Mauricio& Alves Oliveira-Fraga, Lúcia& Soares Silveira, Alda Maria…[et al.]. 2013. Cytokine Pattern of T Lymphocytes in Acute Schistosomiasis mansoni Patients following Treated Praziquantel Therapy. Journal of Parasitology Research،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-507281
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Silveira-Lemos, Denise…[et al.]. Cytokine Pattern of T Lymphocytes in Acute Schistosomiasis mansoni Patients following Treated Praziquantel Therapy. Journal of Parasitology Research No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-507281
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Silveira-Lemos, Denise& Fernandes Costa-Silva, Matheus& Cardoso de Oliveira Silveira, Amanda& Azevedo Batista, Mauricio& Alves Oliveira-Fraga, Lúcia& Soares Silveira, Alda Maria…[et al.]. Cytokine Pattern of T Lymphocytes in Acute Schistosomiasis mansoni Patients following Treated Praziquantel Therapy. Journal of Parasitology Research. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-507281
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507281
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر