Incidence of Pregnancy after Initiation of Antiretroviral Therapy in South Africa : A Retrospective Clinical Cohort Analysis
المؤلفون المشاركون
Westreich, Daniel J.
Majuba, Pappie
MacDonald, Pippa
Maskew, Mhairi
Jaffray, Imogen
Rubel, Dennis
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Little is known about rates of incident pregnancy among HIV-positive women initiating highly active antiretroviral therapy (HAART).
Methods.
We conducted a retrospective clinical cohort study among therapy-naïve women ages 18–45 initiating HAART between 1 April 2004 and 30 September 2009 at an adult HAART clinic in Johannesburg, South Africa.
We used Poisson regression to characterize rates and rate ratios of pregnancy.
Results.
We evaluated 5,996 women who experienced 727 pregnancies during 14,095 person-years at risk.
The overall rate of pregnancy was 5.2 per 100 person-years (95% confidence limits [CL] 4.8, 5.5).
By six years, cumulative incidence of first pregnancy was 22.9% (95% CL 20.6%, 25.4%); among women ages 18–25 at HAART initiation, cumulative incidence was 52.2% (95% CL 35.0%, 71.8%).
The strongest predictor of incidence of pregnancy was age, with women 18–25 having 13.2 times the rate of pregnancy of women ages 40–45 in adjusted analysis.
CD4 counts below 100 and worse adherence to HAART were associated with lower rates of incident pregnancy.
Conclusions.
Women experience high rates of incident pregnancy after HAART initiation.
Understanding which women are most likely to experience pregnancy will help planning and future efforts to understand the implications of pregnancy for response to HAART.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Westreich, Daniel J.& Maskew, Mhairi& Rubel, Dennis& MacDonald, Pippa& Jaffray, Imogen& Majuba, Pappie. 2012. Incidence of Pregnancy after Initiation of Antiretroviral Therapy in South Africa : A Retrospective Clinical Cohort Analysis. Infectious Diseases in Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-507918
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Westreich, Daniel J.…[et al.]. Incidence of Pregnancy after Initiation of Antiretroviral Therapy in South Africa : A Retrospective Clinical Cohort Analysis. Infectious Diseases in Obstetrics and Gynecology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-507918
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Westreich, Daniel J.& Maskew, Mhairi& Rubel, Dennis& MacDonald, Pippa& Jaffray, Imogen& Majuba, Pappie. Incidence of Pregnancy after Initiation of Antiretroviral Therapy in South Africa : A Retrospective Clinical Cohort Analysis. Infectious Diseases in Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-507918
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507918
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر