Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved Ejection Fraction
المؤلفون المشاركون
O’Meara, Eileen
Touyz, Rhian M.
Racine, Normand
Ducharme, Anique
Chabot-Blanchet, Malorie
Gayda, Mathieu
White, Michel
de Denus, Simon
Rouleau, Jean Lucien
Myers, Jonathan N.
Harel, François
Lavoie, Joel
Sirois, Martin G.
Vitiello, Damien
المصدر
International Journal of Vascular Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Changes in cardiopulmonary reserve and biomarkers related to wall stress, inflammation, and oxidative stress concomitantly with the evaluation of peripheral arterial blood flow have not been investigated in patients with heart failure with preserved ejection fraction (HFpEF) compared with healthy subjects (CTL).
Methods and Results.
Eighteen HFpEF patients and 14 CTL were recruited.
Plasma levels of inflammatory and oxidative stress biomarkers were measured at rest.
Brain natriuretic peptide (BNP) was measured at rest and peak exercise.
Cardiopulmonary reserve was assessed using an exercise protocol with gas exchange analyses.
Peripheral arterial blood flow was determined by strain gauge plethysmography.
Peak VO2 (12.0±0.4 versus 19.1±1.1 mL/min/kg, P<0.001) and oxygen uptake efficiency slope (1.55±0.12 versus 2.06±0.14, P<0.05) were significantly decreased in HFpEF patients compared with CTL.
BNP at rest and following stress, C-reactive-protein, interleukin-6, and TBARS were significantly elevated in HFpEF.
Both basal and posthyperemic arterial blood flow were not significantly different between the HFpEF patients and CTL.
Conclusions.
HFpEF exhibits a severe reduction in cardiopulmonary reserve and oxygen uptake efficiency concomitantly with an elevation in a broad spectrum of biomarkers confirming an inflammatory and prooxidative status in patients with HFpEF.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vitiello, Damien& Harel, François& Touyz, Rhian M.& Sirois, Martin G.& Lavoie, Joel& Myers, Jonathan N.…[et al.]. 2014. Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved Ejection Fraction. International Journal of Vascular Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-507939
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vitiello, Damien…[et al.]. Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved Ejection Fraction. International Journal of Vascular Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-507939
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vitiello, Damien& Harel, François& Touyz, Rhian M.& Sirois, Martin G.& Lavoie, Joel& Myers, Jonathan N.…[et al.]. Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved Ejection Fraction. International Journal of Vascular Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-507939
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507939
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر