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Outcome of Combined Hepatocellular and Cholangiocarcinoma of the Liver
المؤلفون المشاركون
Kessinger, Anne
Wang, Jue
Wang, Fen Wei
المصدر
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-09-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The objective of this study was to examine the epidemiology, natural history, and prognostic factors of combined hepatocellular and cholangiocarcinoma (cHCC-CC) using population-based registry.
Methods.
The Surveillance, Epidemiology, and End Results Program database (1973–2004) was used to identify cases of cHCC-CC.
Multivariable logistic regression was used to evaluate factors associated with cancer-directed surgery (CDS).
The influence of CDS on cancer specific survival was evaluated using Kaplan-Meier curves and Cox proportional hazards modeling.
Results.
A total of 380 cases of cHCC-CC were identified, which account for approximately 0.87% of primary liver tumors.
Of all patients, 69.8% of patients had regional or distant stage; 65.6% of patients had poorly or undifferentiated histology.
Only 44.9% of patients with localized disease, received CDS.
By logistic regression analysis, being widowed, advanced stage, and earlier diagnosis year were associated with lower rate of utilization of CDS.
In multivariate analysis, tumor stage, receipt of CDS, and recent year of diagnosis were found to be significant predictors for cancer-specific survival.
Conclusions.
Patients with localized cHCC-CC who are selected for CDS were strongly associated with improved survival.
However, many patients with localized tumors did not receive potentially curative cancer-directed surgery.
Further study is warranted to address the barriers to the delivery of appropriate care to these patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Jue& Wang, Fen Wei& Kessinger, Anne. 2010. Outcome of Combined Hepatocellular and Cholangiocarcinoma of the Liver. Journal of Oncology،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-507949
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Jue…[et al.]. Outcome of Combined Hepatocellular and Cholangiocarcinoma of the Liver. Journal of Oncology No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-507949
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Jue& Wang, Fen Wei& Kessinger, Anne. Outcome of Combined Hepatocellular and Cholangiocarcinoma of the Liver. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-507949
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507949
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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