Patterns of Antimicrobial Resistance in the Causative Organisms of Spontaneous Bacterial Peritonitis : A Single Centre, Six-Year Experience of 1981 Samples
المؤلفون المشاركون
Zare, Elham
Hafezi-Nejad, Nima
Abdollahi, Alireza
Sheikhbahaei, Sara
المصدر
International Journal of Hepatology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background/Aims.
Spontaneous bacterial peritonitis (SBP) is one of the leading causes of morbidity and mortality in patients with cirrhosis.
This study aims to determine the microbial agents of SBP and the pattern of antibiotic resistance, in a large number of ascitic samples.
Methodology.
In a cross-sectional, single center, hospital based study, 1981 consecutive ascitic fluid samples were recruited from 2005 to 2011.
Samples were dichotomized into three-year periods, in order to assess the trend of resistance to the first-line empirical antibiotics.
Results.
SBP was found in 482 (24.33%) of samples, of which 314 (65.15%) were culture positive.
The most prevalent isolated pathogen was E.
coli (33.8%), followed by staphylococcus aureus (8.9%) and Enterococcus (8.6%).
No significant changes in the proportion of gram-negative/gram-positive infections occurred during this period.
A percentage of resistant strains to cefotaxime (62.5%, 85.7%), ceftazidim (73%, 82.1%), ciprofloxacin (30, 59.8%), ofloxacin (36.8%, 50%), and oxacilin (35%, 51.6%) were significantly increased.
E.
coli was most sensitive to imipenem, piperacillin-tazobactam, amikacin, ceftizoxime, and gentamicin.
Conclusions.
The microbial aetiology of SBP remains relatively constant.
However, the resistance rate especially to the first-line recommended antibiotics was significantly increased.
This pattern must be watched closely and taken into account in empirical antibiotic treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sheikhbahaei, Sara& Abdollahi, Alireza& Hafezi-Nejad, Nima& Zare, Elham. 2014. Patterns of Antimicrobial Resistance in the Causative Organisms of Spontaneous Bacterial Peritonitis : A Single Centre, Six-Year Experience of 1981 Samples. International Journal of Hepatology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-508001
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sheikhbahaei, Sara…[et al.]. Patterns of Antimicrobial Resistance in the Causative Organisms of Spontaneous Bacterial Peritonitis : A Single Centre, Six-Year Experience of 1981 Samples. International Journal of Hepatology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-508001
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sheikhbahaei, Sara& Abdollahi, Alireza& Hafezi-Nejad, Nima& Zare, Elham. Patterns of Antimicrobial Resistance in the Causative Organisms of Spontaneous Bacterial Peritonitis : A Single Centre, Six-Year Experience of 1981 Samples. International Journal of Hepatology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-508001
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-508001
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر