Renal Development and Blood Pressure in Offspring from Dams Submitted to High-Sodium Intake during Pregnancy and Lactation
المؤلفون المشاركون
Balbi, Ana Paula C.
Francescato, Heloísa D. C.
Coimbra, Terezila M.
Marin, Evelyn C. S.
Costa, Roberto S.
المصدر
International Journal of Nephrology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Exposure to an adverse environment in utero appears to programme physiology and metabolism permanently, with long-term consequences for health of the fetus or offspring.
It was observed that the offspring from dams submitted to high-sodium intake during pregnancy present disturbances in renal development and in blood pressure.
These alterations were associated with lower plasma levels of angiotensin II (AII) and changes in renal AII receptor I (AT1) and mitogen-activated protein kinase (MAPK) expressions during post natal kidney development.
Clinical and experimental evidence show that the renin-angiotensin system (RAS) participates in renal development.
Many effects of AII are mediated through MAPK pathways.
Extracellular signal-regulated protein kinases (ERKs) play a pivotal role in cellular proliferation and differentiation.
In conclusion, high-sodium intake during pregnancy and lactation can provoke disturbances in renal development in offspring leading to functional and structural alterations that persist in adult life.
These changes can be related at least in part with the decrease in RAS activity considering that this system has an important role in renal development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Coimbra, Terezila M.& Francescato, Heloísa D. C.& Balbi, Ana Paula C.& Marin, Evelyn C. S.& Costa, Roberto S.. 2012. Renal Development and Blood Pressure in Offspring from Dams Submitted to High-Sodium Intake during Pregnancy and Lactation. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-508122
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Coimbra, Terezila M.…[et al.]. Renal Development and Blood Pressure in Offspring from Dams Submitted to High-Sodium Intake during Pregnancy and Lactation. International Journal of Nephrology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-508122
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Coimbra, Terezila M.& Francescato, Heloísa D. C.& Balbi, Ana Paula C.& Marin, Evelyn C. S.& Costa, Roberto S.. Renal Development and Blood Pressure in Offspring from Dams Submitted to High-Sodium Intake during Pregnancy and Lactation. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-508122
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-508122
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر