Adsorption and Desorption of Bioactive Proteins on Hydroxyapatite for Protein Delivery Systems

المؤلفون المشاركون

Kojima, Chie
Watanabe, Kenji

المصدر

Journal of Drug Delivery

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-03-05

دولة النشر

مصر

عدد الصفحات

4

التخصصات الرئيسية

الطب البشري

الملخص EN

Hydroxyapatite (HA) is a precursor of bone and has been studied as a biomaterial.

We attempted HA to apply to protein delivery systems.

In this study, the association and dissociation properties of two types of bioactive proteins, cytochrom c and insulin, to HA were investigated.

Cytochrom c was less associated with HA than insulin, which was easily released from it.

However, the release of insulin from HA was slow.

Insulin was released from HA at pH 7.4 more rapidly than at pH 3.

The association and dissociation properties might be influenced by the size, solubility and net charge of protein.

HA is a potential protein carrier with controlled release.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kojima, Chie& Watanabe, Kenji. 2012. Adsorption and Desorption of Bioactive Proteins on Hydroxyapatite for Protein Delivery Systems. Journal of Drug Delivery،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-509265

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kojima, Chie& Watanabe, Kenji. Adsorption and Desorption of Bioactive Proteins on Hydroxyapatite for Protein Delivery Systems. Journal of Drug Delivery No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-509265

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kojima, Chie& Watanabe, Kenji. Adsorption and Desorption of Bioactive Proteins on Hydroxyapatite for Protein Delivery Systems. Journal of Drug Delivery. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-509265

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-509265