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Rapid Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in HIV-Infected Patients. Comparison of LED Fluorescent Microscopy and the GeneXpert MTBRIF Assay in a District Hospital in India
المؤلفون المشاركون
Naik, Praveen Kumar
Alvarez-Uria, Gerardo
Reddy, Raghuprakash
Midde, Manoranjan
Reddy, Srinivasulu
Azcona, Jose M.
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-26
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
HIV-related tuberculosis is difficult to diagnose and is associated with high morbidity and mortality.
Recently, the World Health Organization has endorsed the GeneXpert MTB/RIF (Xpert) assay for the diagnosis of pulmonary tuberculosis in HIV-infected patients from developing countries, but information about the use of Xpert for the diagnosis of extrapulmonary tuberculosis is scarce.
In this study, we compared the performance of light-emitting diode (LED) auramine fluorescent microscopy and the Xpert assay for the diagnosis of tuberculosis in HIV infected patients in a district hospital of India.
Although at higher cost, Xpert outperformed LED fluorescent microscopy in all type of specimens, especially in cerebrospinal fluid where the number of positive results was increased 11 times.
Pleural fluid, ascitic fluid, pus, and stool specimens also yielded positive results with the Xpert assay.
When collecting two additional early-morning sputum samples, the increase of the number of positive results with the Xpert assay was lower than previously reported for HIV infected patients.
Rifampicin resistance was observed in 2.2% of the cases.
The results of this study show that the Xpert assay can dramatically improve the rapid diagnosis of tuberculous meningitis and other types of extrapulmonary tuberculosis of HIV infected patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alvarez-Uria, Gerardo& Azcona, Jose M.& Midde, Manoranjan& Naik, Praveen Kumar& Reddy, Srinivasulu& Reddy, Raghuprakash. 2012. Rapid Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in HIV-Infected Patients. Comparison of LED Fluorescent Microscopy and the GeneXpert MTBRIF Assay in a District Hospital in India. Tuberculosis Research and Treatment،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-509327
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alvarez-Uria, Gerardo…[et al.]. Rapid Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in HIV-Infected Patients. Comparison of LED Fluorescent Microscopy and the GeneXpert MTBRIF Assay in a District Hospital in India. Tuberculosis Research and Treatment No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-509327
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alvarez-Uria, Gerardo& Azcona, Jose M.& Midde, Manoranjan& Naik, Praveen Kumar& Reddy, Srinivasulu& Reddy, Raghuprakash. Rapid Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in HIV-Infected Patients. Comparison of LED Fluorescent Microscopy and the GeneXpert MTBRIF Assay in a District Hospital in India. Tuberculosis Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-509327
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509327
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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