Germinoma with Involvement of Midline and Off-Midline Intracranial Structures
المؤلفون المشاركون
Loto, Monica Graciela
González Abbati, Santiago
Misiunas, Alejandro
Torino, Rafael
Danilowicz, Karina
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-09
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Germinomas are malignant intracranial germ tumors, usually found in suprasellar regions.
Less than 10% are localized in off-middle structures, and synchronous involvement of both structures has only exceptionally been published.
A case of an 18-year-old male patient with progressive right-sided hemiparesis and panhypopituitarism was reviewed.
Brain MRI showed a solid mass involving pituitary and hypothalamus with thickening of pituitary stalk, high intensity lesions on T2-weighted imaging in left internal capsule, caudate nucleus, globus pallidus, and mild atrophy of the left internal capsule and cerebral peduncle.
Nonadenomatous lesions were considered in the differential diagnosis.
Alfa-fetoprotein (AFP) levels were negative in both serum and cerebrospinal fluid (CSF), while β-human chorionic gonadotrophin (β-HCG) levels were slightly increased in CSF.
A transsphenoidal biopsy identified a germinoma.
Four cycles of chemotherapy with bleomicine, etoposide, and cysplatin were given, followed by radiotherapy, but patients died due to a recidiva.
Conclusion.
Germinoma must be considered in patients with insipidus diabetes with a sellar mass with thickening of pituitary stalk; and ectopic germinoma must be suspected in patients with slowly progressive hemiparesis with cerebral hemiatrophy.
Even with a rare condition, colocalization of midline and off-midline germinoma must be suspected in the presence of these typical signs of both localizations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Loto, Monica Graciela& Danilowicz, Karina& González Abbati, Santiago& Torino, Rafael& Misiunas, Alejandro. 2014. Germinoma with Involvement of Midline and Off-Midline Intracranial Structures. Case Reports in Endocrinology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-509614
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Loto, Monica Graciela…[et al.]. Germinoma with Involvement of Midline and Off-Midline Intracranial Structures. Case Reports in Endocrinology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-509614
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Loto, Monica Graciela& Danilowicz, Karina& González Abbati, Santiago& Torino, Rafael& Misiunas, Alejandro. Germinoma with Involvement of Midline and Off-Midline Intracranial Structures. Case Reports in Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-509614
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509614
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر