Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation
المؤلفون المشاركون
Korac, Aleksandra
Markelic, Milica
Stancic, Ana
Velickovic, Ksenija
Vucetic, Milica
Buzadzic, Biljana
Golic, Igor
Otasevic, Vesna
Jankovic, Aleksandra
Korac, Bato
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-24
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The expression profiles of adiponectin, resistin, 5′-AMP-activated protein kinase α (AMPKα), hypoxia-inducible factor-1α (HIF-1α), and key enzymes of glucose and fatty acid metabolism and oxidative phosphorylation in rat retroperitoneal white adipose tissue (RpWAT) during 45-day cold acclimation were examined.
After transient suppression on day 1, adiponectin protein level increased following sustained cold exposure.
In parallel, on day 1, the protein level of HIF-1α was strongly induced and AMPKα suppressed, while afterwards the reverse was seen.
What is more, after an initial decrease on day 1, a sequential increase in pyruvate dehydrogenase, acyl-CoA dehydrogenase, cytochrome c oxidase, and ATP synthase and a decrease in acetyl-CoA carboxylase (from day 3) were observed.
Similar to adiponectin, protein level of resistin showed a biphasic profile: it increased after days 1, 3, and 7 and decreased below the control after 21 days of cold-acclimation.
In summary, the data suggest that adiponectin and resistin are important integrators of RpWAT metabolic response and roles it plays during cold acclimation.
It seems that AMPKα mediate adiponectin effects on metabolic remodeling RpWAT during cold acclimation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jankovic, Aleksandra& Korac, Aleksandra& Buzadzic, Biljana& Otasevic, Vesna& Stancic, Ana& Vucetic, Milica…[et al.]. 2013. Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation. Journal of Obesity،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-509674
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jankovic, Aleksandra…[et al.]. Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation. Journal of Obesity No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-509674
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jankovic, Aleksandra& Korac, Aleksandra& Buzadzic, Biljana& Otasevic, Vesna& Stancic, Ana& Vucetic, Milica…[et al.]. Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation. Journal of Obesity. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-509674
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509674
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر