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Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults
المؤلفون المشاركون
Gothe, Neha P.
Basak, Chandramallika
Wojcicki, Thomas R.
Kramer, Arthur F.
Verstynen, Timothy D.
Miller, Destiny L.
Szabo, Amanda
Fanning, Jason
Prakash, Ruchika Shaurya
Olson, Erin A.
McAuley, Edward
Voss, Michelle W.
Lynch, Brighid
Chaddock, Laura
Erickson, Kirk I.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-31
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
The basal ganglia play a central role in regulating the response selection abilities that are critical for mental flexibility.
In neocortical areas, higher cardiorespiratory fitness levels are associated with increased gray matter volume, and these volumetric differences mediate enhanced cognitive performance in a variety of tasks.
Here we examine whether cardiorespiratory fitness correlates with the volume of the subcortical nuclei that make up the basal ganglia and whether this relationship predicts cognitive flexibility in older adults.
Structural MRI was used to determine the volume of the basal ganglia nuclei in a group of older, neurologically healthy individuals (mean age 66 years, N=179).
Measures of cardiorespiratory fitness (VO2max), cognitive flexibility (task switching), and attentional control (flanker task) were also collected.
Higher fitness levels were correlated with higher accuracy rates in the Task Switching paradigm.
In addition, the volume of the caudate nucleus, putamen, and globus pallidus positively correlated with Task Switching accuracy.
Nested regression modeling revealed that caudate nucleus volume was a significant mediator of the relationship between cardiorespiratory fitness, and task switching performance.
These findings indicate that higher cardiorespiratory fitness predicts better cognitive flexibility in older adults through greater grey matter volume in the dorsal striatum.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Verstynen, Timothy D.& Lynch, Brighid& Miller, Destiny L.& Voss, Michelle W.& Prakash, Ruchika Shaurya& Chaddock, Laura…[et al.]. 2012. Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults. Journal of Aging Research،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-509825
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Verstynen, Timothy D.…[et al.]. Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults. Journal of Aging Research No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-509825
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Verstynen, Timothy D.& Lynch, Brighid& Miller, Destiny L.& Voss, Michelle W.& Prakash, Ruchika Shaurya& Chaddock, Laura…[et al.]. Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults. Journal of Aging Research. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-509825
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509825
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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