To Bind or to Let Loose : Effectiveness of Sodium Polystyrene Sulfonate in Decreasing Serum Potassium

المؤلفون المشاركون

Karachiwala, Hatim
Noviasky, John
Lehmann, David F.
Sandal, Shaifali
Wang, Dongliang
Elliott, William C.

المصدر

International Journal of Nephrology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-12-27

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Background.

The use of sodium polystyrene sulfonate in decreasing serum potassium has recently been questioned due to the lack of documented effectiveness.

Methods.

A retrospective cohort analysis of all hospitalized patients who received sodium polystyrene sulfonate over four months was performed.

The change in serum potassium was noted over a period of 24 hours.

Patients who received any other form of potassium-altering drug or treatment were excluded.

Results.

The administration of sodium polystyrene sulfonate reduced serum potassium by 16.7% (P<0.001) as compared to the baseline serum potassium over a period of 24 hours.

During this same time, no change in serum creatinine was identified (P=0.73).

In addition, there was no correlation between potassium and creatinine change (r2 = 0.0004 and P=0.99).

Patients with higher initial serum potassium (≥5.6 mEq/L) reduced their potassium concentration 4% more than those with initial serum potassium of <5.6 mEq/L; however, this reduction did not reach statistical significance (P=0.32).

There was no significant difference in the effectiveness of 15 gm and 30 gm resin preparation (P=0.54).

Thirteen deaths were noted in our cohort, of which one death was due to ischemic colitis.

Conclusion.

We conclude that sodium polystyrene sulfonate is effective in lowering serum potassium.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sandal, Shaifali& Karachiwala, Hatim& Noviasky, John& Wang, Dongliang& Elliott, William C.& Lehmann, David F.. 2012. To Bind or to Let Loose : Effectiveness of Sodium Polystyrene Sulfonate in Decreasing Serum Potassium. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-509904

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sandal, Shaifali…[et al.]. To Bind or to Let Loose : Effectiveness of Sodium Polystyrene Sulfonate in Decreasing Serum Potassium. International Journal of Nephrology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-509904

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sandal, Shaifali& Karachiwala, Hatim& Noviasky, John& Wang, Dongliang& Elliott, William C.& Lehmann, David F.. To Bind or to Let Loose : Effectiveness of Sodium Polystyrene Sulfonate in Decreasing Serum Potassium. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-509904

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-509904