Clinical Predictors of Mortality in Adults with Intellectual Disabilities with and without Down Syndrome
المؤلفون المشاركون
Bennett, Vernon
Thorpe, Lilian
Pahwa, Punam
Kirk, Andrew
Nanson, Josephine
المصدر
Current Gerontology and Geriatrics Research
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-16
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Mood, baseline functioning, and cognitive abilities as well as psychotropic medications may contribute to mortality in adults with and without Down Syndrome (DS).
Methods.
Population-based (nonclinical), community-dwelling adults with intellectual disabilities (IDs) were recruited between 1995 and 2000, assessed individually for 1–4 times, and then followed by yearly phone calls.
Results.
360 participants (116 with DS and 244 without DS) were followed for an average of 12.9 years (range 0–16.1 years as of July 2011).
108 people died during the course of the followup, 65 males (31.9% of all male participants) and 43 females (27.6% of all female participants).
Cox proportional hazards modeling showed that baseline practical skills, seizures, anticonvulsant use, depressive symptoms, and cognitive decline over the first six years all significantly contributed to mortality, as did a diagnosis of DS, male gender, and higher age at study entry.
Analysis stratified by DS showed interesting differences in mortality predictors.
Conclusion.
Although adults with DS have had considerable improvements in life expectancy over time, they are still disadvantaged compared to adults with ID without DS.
Recognition of potentially modifiable factors such as depression may decrease this risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Thorpe, Lilian& Pahwa, Punam& Bennett, Vernon& Kirk, Andrew& Nanson, Josephine. 2012. Clinical Predictors of Mortality in Adults with Intellectual Disabilities with and without Down Syndrome. Current Gerontology and Geriatrics Research،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-510238
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Thorpe, Lilian…[et al.]. Clinical Predictors of Mortality in Adults with Intellectual Disabilities with and without Down Syndrome. Current Gerontology and Geriatrics Research No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-510238
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Thorpe, Lilian& Pahwa, Punam& Bennett, Vernon& Kirk, Andrew& Nanson, Josephine. Clinical Predictors of Mortality in Adults with Intellectual Disabilities with and without Down Syndrome. Current Gerontology and Geriatrics Research. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-510238
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-510238
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر