Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints
المؤلفون المشاركون
Brown, Jesse A.
Bookheimer, Susan Y.
Henning, Susanne M.
Renner, Brian A.
Ekstrom, Arne
Moody, Teena
Jones, Mike
Li, Zhaoping
Small, Gary W.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-22
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Despite increasing emphasis on the potential of dietary antioxidants in preventing memory loss and on diet as a precursor of neurological health, rigorous studies investigating the cognitive effects of foods and their components are rare.
Recent animal studies have reported memory and other cognitive benefits of polyphenols, found abundantly in pomegranate juice.
We performed a preliminary, placebo-controlled randomized trial of pomegranate juice in older subjects with age-associated memory complaints using memory testing and functional brain activation (fMRI) as outcome measures.
Thirty-two subjects (28 completers) were randomly assigned to drink 8 ounces of either pomegranate juice or a flavor-matched placebo drink for 4 weeks.
Subjects received memory testing, fMRI scans during cognitive tasks, and blood draws for peripheral biomarkers before and after the intervention.
Investigators and subjects were all blind to group membership.
After 4 weeks, only the pomegranate group showed a significant improvement in the Buschke selective reminding test of verbal memory and a significant increase in plasma trolox-equivalent antioxidant capacity (TEAC) and urolithin A-glucuronide.
Furthermore, compared to the placebo group, the pomegranate group had increased fMRI activity during verbal and visual memory tasks.
While preliminary, these results suggest a role for pomegranate juice in augmenting memory function through task-related increases in functional brain activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bookheimer, Susan Y.& Renner, Brian A.& Ekstrom, Arne& Li, Zhaoping& Henning, Susanne M.& Brown, Jesse A.…[et al.]. 2013. Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-510372
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bookheimer, Susan Y.…[et al.]. Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-14.
https://search.emarefa.net/detail/BIM-510372
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bookheimer, Susan Y.& Renner, Brian A.& Ekstrom, Arne& Li, Zhaoping& Henning, Susanne M.& Brown, Jesse A.…[et al.]. Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-510372
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-510372
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر