Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration
المؤلفون المشاركون
Hamamah, Samir
Dechaud, Hervé
Entezami, Frida
Assou, Said
Perrochia, Hélène
Haouzi, Delphine
Hugues, Jean-Noel
Gala, Anna
Bissonnette, Laurence
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-28
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The impact of a premature elevation of serum progesterone level, the day of hCG administration in patients under controlled ovarian stimulation during IVF procedure, on human endometrial receptivity is still debated.
In the present study, we investigated the endometrial gene expression profile shifts during the prereceptive and receptive secretory stage in patients with normal and elevated serum progesterone level on the day of hCG administration in fifteen patients under stimulated cycles.
Then, specific biomarkers of endometrial receptivity in these two groups of patients were tested.
Endometrial biopsies were performed on oocyte retrieval day and on day 3 of embryo transfer, respectively, for each patient.
Samples were analysed using DNA microarrays and qRT-PCR.
The endometrial gene expression shift from the prereceptive to the receptive stage was altered in patients with high serum progesterone level (>1.5 ng/mL) on hCG day, suggesting accelerated endometrial maturation during the periovulation period.
This was confirmed by the functional annotation of the differentially expressed genes as it showed downregulation of cell cycle-related genes.
Conversely, the profile of endometrial receptivity was comparable in both groups.
Premature progesterone rise alters the endometrial gene expression shift between the prereceptive and the receptive stage but does not affect endometrial receptivity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Haouzi, Delphine& Bissonnette, Laurence& Gala, Anna& Assou, Said& Entezami, Frida& Perrochia, Hélène…[et al.]. 2014. Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-510905
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Haouzi, Delphine…[et al.]. Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-510905
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Haouzi, Delphine& Bissonnette, Laurence& Gala, Anna& Assou, Said& Entezami, Frida& Perrochia, Hélène…[et al.]. Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-510905
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-510905
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر