![](/images/graphics-bg.png)
Immunomodulatory Effects of Danshen (Salvia miltiorrhiza) in BALBc Mice
المؤلفون المشاركون
Lawrence, David A.
Gao, Donghong
Mendoza, Alvaro
Lu, Shijun
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-16
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Danshen, the root and rhizome of Salvia miltiorrhiza Bge, a Traditional Chinese Medicine, especially for cardiovascular and cerebrovascular diseases, has unique immunomodulatory effects.
Danshen is capable of anti-inflammation and antiallergy, which are immunosuppressive activities, whereas it is also able to promote immunity against cancer, viruses, and bacteria.
Most previous reports were performed with use of a purified compound or compounds of Danshen.
Since there are more than twenty active compounds in Danshen, it is very difficult to predict that one compound will act the same way when it is combined with other compounds.
In order to overcome this limitation, we used the crude form of Danshen to study its immunomodulatory effects in a mouse model.
The mice were fed daily diet supplements of Danshen for three months and then tested for their immunity, including leukocyte subsets in peripheral blood, humoral and cell-mediated immune responses, and host defenses against a Listeria monocytogenes (LM) infection.
Different doses of Danshen caused different immunomodulatory effects.
Danshen at 0.5% decreased serum IgE production in BALB/c mice; 1% Danshen promoted cell-mediated immunity; Danshen at 0.5 and 1% inhibited the production of oxygen free radicals in liver and spleen and NO production in liver; 2% Danshen enhanced the host resistance against LM with increased numbers of peripheral monocytes and natural killer (NK) cells and decreased production of IL-1β and NO.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gao, Donghong& Mendoza, Alvaro& Lu, Shijun& Lawrence, David A.. 2012. Immunomodulatory Effects of Danshen (Salvia miltiorrhiza) in BALBc Mice. ISRN Inflammation،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-511114
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gao, Donghong…[et al.]. Immunomodulatory Effects of Danshen (Salvia miltiorrhiza) in BALBc Mice. ISRN Inflammation No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-511114
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gao, Donghong& Mendoza, Alvaro& Lu, Shijun& Lawrence, David A.. Immunomodulatory Effects of Danshen (Salvia miltiorrhiza) in BALBc Mice. ISRN Inflammation. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-511114
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511114
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)