System Consolidation of Spatial Memories in Mice : Effects of Enriched Environment
المؤلفون المشاركون
Braschi, Chiara
Cintoli, Simona
Mastrogiacomo, Rosa
Berardi, Nicoletta
Bonaccorsi, Joyce
Pizzorusso, Tommaso
Baldanzi, Sigrid
Cenni, Maria Cristina
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-07
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Environmental enrichment (EE) is known to enhance learning and memory.
Declarative memories are thought to undergo a first rapid and local consolidation process, followed by a prolonged process of system consolidation, which consist in a time-dependent gradual reorganization of brain regions supporting remote memory storage and crucial for the formation of enduring memories.
At present, it is not known whether EE can affect the process of declarative memory system consolidation.
We characterized the time course of hippocampal and cortical activation following recall of progressively more remote spatial memories.
Wild-type mice either exposed to EE for 40 days or left in standard environment were subjected to spatial learning in the Morris water maze and to the probe test 1, 10, 20, 30, and 50 days after learning.
Following the probe test, regional expression of the inducible immediate early gene c-Fos was mapped by immunohistochemistry, as an indicator of neuronal activity.
We found that activation of the medial prefrontal cortex (mPFC), suggested to have a privileged role in processing remote spatial memories, was evident at shorter time intervals after learning in EE mice; in addition, EE induced the progressive activation of a distributed cortical network not activated in non-EE mice.
This suggests that EE not only accelerates the process of mPFC recruitment but also recruits additional cortical areas into the network supporting remote spatial memories.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bonaccorsi, Joyce& Cintoli, Simona& Mastrogiacomo, Rosa& Baldanzi, Sigrid& Braschi, Chiara& Pizzorusso, Tommaso…[et al.]. 2013. System Consolidation of Spatial Memories in Mice : Effects of Enriched Environment. Neural Plasticity،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-511231
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bonaccorsi, Joyce…[et al.]. System Consolidation of Spatial Memories in Mice : Effects of Enriched Environment. Neural Plasticity No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-511231
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bonaccorsi, Joyce& Cintoli, Simona& Mastrogiacomo, Rosa& Baldanzi, Sigrid& Braschi, Chiara& Pizzorusso, Tommaso…[et al.]. System Consolidation of Spatial Memories in Mice : Effects of Enriched Environment. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-511231
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511231
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر