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Antidepressant-Like Effect of Ilex paraguariensis in Rats
المؤلفون المشاركون
Busanello, Alcindo
Augusti Boligon, Aline
Libardoni, Milena
Leal, Caroline Queiroz
Lehmen, Tássia Fontana
Neto, Francisco Waldomiro Schreiner
Fachinetto, Roselei
Peroza, Luis Ricardo
Cattani, Vitória Berg
Reis, Elizete De Moraes
Athayde, Margareth Linde
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-04
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
In this study, we investigated the possible antidepressant-like effect of I.
paraguariensis in rats.
Rats were treated for four weeks with an aqueous extract of I.
paraguariensis in drinking water, following the traditional preparation of this beverage.
After the period of treatment, behavioral (elevated plus-maze, open field test, and forced swimming test) and biochemical parameters (lipid peroxidation assay, thiol content, vitamin C levels, and monoamine oxidase activity) were evaluated.
Animals were also analyzed on forced swimming test after 24 hours of I.
paraguariensis intake.
An additional group was injected with selegiline 24 hours and 30 minutes before forced swimming test as positive control.
HPLC analysis revealed the profile of I.
paraguariensis extract.
I.
paraguariensis reduced the immobility time on forced swimming test without significant changes in locomotor activity in the open field test.
Any anxiolytic/anxiogenic effect of I.
paraguariensis was observed in rats through the elevated plus-maze test.
The antidepressant-like effect of I.
paraguariensis was not accompanied by inhibitory effect on monoamine oxidase activity.
There were no significant alterations on lipid peroxidation, thiol content, and vitamin C levels among the groups.
In conclusion, aqueous extract of I.
paraguariensis decreases the time of immobility in rats suggesting an antidepressant-like effect.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Reis, Elizete De Moraes& Neto, Francisco Waldomiro Schreiner& Cattani, Vitória Berg& Peroza, Luis Ricardo& Busanello, Alcindo& Leal, Caroline Queiroz…[et al.]. 2014. Antidepressant-Like Effect of Ilex paraguariensis in Rats. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-511415
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Reis, Elizete De Moraes…[et al.]. Antidepressant-Like Effect of Ilex paraguariensis in Rats. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-511415
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Reis, Elizete De Moraes& Neto, Francisco Waldomiro Schreiner& Cattani, Vitória Berg& Peroza, Luis Ricardo& Busanello, Alcindo& Leal, Caroline Queiroz…[et al.]. Antidepressant-Like Effect of Ilex paraguariensis in Rats. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-511415
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511415
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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