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Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable
المؤلفون المشاركون
Wood-Baker, Richard
Soltani, Amir
Muller, Hans Konrad
Walters, E. Haydn
Sohal, Sukhwinder S.
Reid, David
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-27
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background and Objective.
Using Collagen IV staining, we have previously reported that the reticular basement membrane (Rbm) is hypervascular and the lamina propria (LP) is hypovascular in COPD airways.
This study compared Collagen IV staining with vessels marked with anti-Factor VIII and examined vessel permeability in bronchial biopsies from COPD and normal subjects using albumin staining.
Results.
Anti-Collagen IV antibody detected more vessels in the Rbm (P=0.002) and larger vessels in both Rbm (P<0.001) and LP (P=0.003) compared to Factor VIII.
COPD airways had more vessels (with greater permeability) in the Rbm (P=0.01) and fewer vessels (with normal permeability) in the LP compared to controls with both Collagen IV and Factor VIII antibodies (P=0.04 and P=0.01).
Conclusion.
Rbm vessels were increased in number and were hyperpermeable in COPD airways.
Anti-Collagen IV and anti-Factor VIII antibodies did not uniformly detect the same vessel populations; the first is likely to reflect larger and older vessels with the latter reflecting smaller, younger vessels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Soltani, Amir& Wood-Baker, Richard& Sohal, Sukhwinder S.& Muller, Hans Konrad& Reid, David& Walters, E. Haydn. 2012. Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable. Journal of Allergy،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-511434
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Soltani, Amir…[et al.]. Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable. Journal of Allergy No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-511434
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Soltani, Amir& Wood-Baker, Richard& Sohal, Sukhwinder S.& Muller, Hans Konrad& Reid, David& Walters, E. Haydn. Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable. Journal of Allergy. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-511434
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511434
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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