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Health Promoting Effects of Brassica-Derived Phytochemicals : From Chemopreventive and Anti-Inflammatory Activities to Epigenetic Regulation
المؤلفون المشاركون
Wagner, Anika Eva
Terschluesen, Anna Maria
Rimbach, Gerald
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-23
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
A high intake of brassica vegetables may be associated with a decreased chronic disease risk.
Health promoting effects of Brassicaceae have been partly attributed to glucosinolates and in particular to their hydrolyzation products including isothiocyanates.
In vitro and in vivo studies suggest a chemopreventive activity of isothiocyanates through the redox-sensitive transcription factor Nrf2.
Furthermore, studies in cultured cells, in laboratory rodents, and also in humans support an anti-inflammatory effect of brassica-derived phytochemicals.
However, the underlying mechanisms of how these compounds mediate their health promoting effects are yet not fully understood.
Recent findings suggest that brassica-derived compounds are regulators of epigenetic mechanisms.
It has been shown that isothiocyanates may inhibit histone deacetylase transferases and DNA-methyltransferases in cultured cells.
Only a few papers have dealt with the effect of brassica-derived compounds on epigenetic mechanisms in laboratory animals, whereas data in humans are currently lacking.
The present review aims to summarize the current knowledge regarding the biological activities of brassica-derived phytochemicals regarding chemopreventive, anti-inflammatory, and epigenetic pathways.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wagner, Anika Eva& Terschluesen, Anna Maria& Rimbach, Gerald. 2013. Health Promoting Effects of Brassica-Derived Phytochemicals : From Chemopreventive and Anti-Inflammatory Activities to Epigenetic Regulation. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-511956
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wagner, Anika Eva…[et al.]. Health Promoting Effects of Brassica-Derived Phytochemicals : From Chemopreventive and Anti-Inflammatory Activities to Epigenetic Regulation. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-511956
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wagner, Anika Eva& Terschluesen, Anna Maria& Rimbach, Gerald. Health Promoting Effects of Brassica-Derived Phytochemicals : From Chemopreventive and Anti-Inflammatory Activities to Epigenetic Regulation. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-511956
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511956
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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