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Maintenance Therapy with Partially Hydrolyzed Guar Gum in the Conservative Treatment of Chronic Anal Fissure : Results of a Prospective, Randomized Study
المؤلفون المشاركون
Grassi, Roberto
Renzi, Adolfo
Di Martino, Natale
Iacobellis, Francesca
Brillantino, Antonio
Izzo, Giuseppe
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-25
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
This study was designed to evaluate the role of maintenance therapy with partially hydrolyzed guar gum (PHGG) after topical application of glyceryl trinitrate (GTN) in the conservative treatment of chronic anal fissure (CAF).
Methods.
From all the patients with CAF observed during the study period, 165 subjects with healed CAF after standard therapy with topical GTN 0.4% ointment were randomized to receive (group II) or not (group I) maintenance therapy with PHGG for 10 months.
Clinical and manometric followup was carried out 6 and 12 months after treatment.
Results.
At six-month followup, median visual analogue scale score was significantly higher in group I if compared with group II.
The success and recurrence rate at 12-month followup were, respectively, 38.3% (28/73) in group I versus 58.5% (41/70) in group II (P=0.019; Fisher’s exact test) and 30.2% (13/43) in group I versus 14.5% (7/48) in group II (P=0.0047; Fisher’s exact test).
Conclusion.
The maintenance therapy with PHGG in patients with healed CAF after chemical sphincterotomy by topical application of GTN 0.4% ointment seems associated with a significant reduction of recurrence rate and with a significant increase of success rate at 12-month followup.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Brillantino, Antonio& Iacobellis, Francesca& Izzo, Giuseppe& Di Martino, Natale& Grassi, Roberto& Renzi, Adolfo. 2014. Maintenance Therapy with Partially Hydrolyzed Guar Gum in the Conservative Treatment of Chronic Anal Fissure : Results of a Prospective, Randomized Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-511995
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Brillantino, Antonio…[et al.]. Maintenance Therapy with Partially Hydrolyzed Guar Gum in the Conservative Treatment of Chronic Anal Fissure : Results of a Prospective, Randomized Study. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-511995
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Brillantino, Antonio& Iacobellis, Francesca& Izzo, Giuseppe& Di Martino, Natale& Grassi, Roberto& Renzi, Adolfo. Maintenance Therapy with Partially Hydrolyzed Guar Gum in the Conservative Treatment of Chronic Anal Fissure : Results of a Prospective, Randomized Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-511995
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511995
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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