Refractory Uveitis in Patient with Castleman Disease Successfully Treated with Tocilizumab
المؤلفون المشاركون
Oshitari, Toshiyuki
Baba, Takayuki
Itami, Makiko
Tobe, Aya
Yamamoto, Shuichi
Yotsukura, Jiro
Kajita, Fusae
المصدر
Case Reports in Ophthalmological Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-06
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Although multicentric Castleman disease is a rare but life-threatening disease, eye complications are extremely uncommon.
We present a case of refractory uveitis accompanied with Castleman disease successfully treated with tocilizumab.
A 58-year-old man with Castleman disease was introduced for refractory uveitis to Chiba University Hospital.
Large cells were detected in the anterior chamber and increased vascular permeability of retinal vessels has been found in both eyes.
Although the patient was treated with oral and eye drop steroid treatment, the uveitis symptoms had not decreased.
The serum levels of CRP and IL-6 were increased.
The level of IL-6 concentration in the anterior chamber was the same as the serum level of IL-6.
The humanized anti-IL-6 receptor-antibody (tocilizumab) was administrated for the patient because of poor general condition.
After tocilizumab treatment, large cells in the anterior chamber were undetectable and vascular permeability was improved in FA.
The serum levels of CRP and IL-6 decreased and the general condition improved.
The side effect of tocilizumab was not observed during the treatment.
Tocilizumab treatment was significantly effective for uveitis accompanied with Castleman disease.
Although it is extremely rare, uveitis accompanied with Castleman disease may be one of the hallmarks to consider tocilizumab treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oshitari, Toshiyuki& Kajita, Fusae& Tobe, Aya& Itami, Makiko& Yotsukura, Jiro& Baba, Takayuki…[et al.]. 2012. Refractory Uveitis in Patient with Castleman Disease Successfully Treated with Tocilizumab. Case Reports in Ophthalmological Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-512186
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oshitari, Toshiyuki…[et al.]. Refractory Uveitis in Patient with Castleman Disease Successfully Treated with Tocilizumab. Case Reports in Ophthalmological Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-512186
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oshitari, Toshiyuki& Kajita, Fusae& Tobe, Aya& Itami, Makiko& Yotsukura, Jiro& Baba, Takayuki…[et al.]. Refractory Uveitis in Patient with Castleman Disease Successfully Treated with Tocilizumab. Case Reports in Ophthalmological Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-512186
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-512186
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر