Application of Genetic Algorithm for Discovery of Core Effective Formulae in TCM Clinical Data
المؤلفون المشاركون
Poon, Simon
Chen, Peiqi
Sze, Daniel Man-yuen
Wang, Shaomo
Jiao, Lijing
Yang, Ming
Xu, Ling
Poon, Josiah
Cui, Lizhi
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-30
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Research on core and effective formulae (CEF) does not only summarize traditional Chinese medicine (TCM) treatment experience, it also helps to reveal the underlying knowledge in the formulation of a TCM prescription.
In this paper, CEF discovery from tumor clinical data is discussed.
The concepts of confidence, support, and effectiveness of the CEF are defined.
Genetic algorithm (GA) is applied to find the CEF from a lung cancer dataset with 595 records from 161 patients.
The results had 9 CEF with positive fitness values with 15 distinct herbs.
The CEF have all had relative high average confidence and support.
A herb-herb network was constructed and it shows that all the herbs in CEF are core herbs.
The dataset was divided into CEF group and non-CEF group.
The effective proportions of former group are significantly greater than those of latter group.
A Synergy index (SI) was defined to evaluate the interaction between two herbs.
There were 4 pairs of herbs with high SI values to indicate the synergy between the herbs.
All the results agreed with the TCM theory, which demonstrates the feasibility of our approach.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Ming& Poon, Josiah& Wang, Shaomo& Jiao, Lijing& Poon, Simon& Cui, Lizhi…[et al.]. 2013. Application of Genetic Algorithm for Discovery of Core Effective Formulae in TCM Clinical Data. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-512438
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Ming…[et al.]. Application of Genetic Algorithm for Discovery of Core Effective Formulae in TCM Clinical Data. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-512438
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Ming& Poon, Josiah& Wang, Shaomo& Jiao, Lijing& Poon, Simon& Cui, Lizhi…[et al.]. Application of Genetic Algorithm for Discovery of Core Effective Formulae in TCM Clinical Data. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-512438
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-512438
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر