Serum levels of adhesion molecules in lichen planus and the effect of associated hepatitis C virus
العناوين الأخرى
مستوى الجزيئات اللاصقة في المصل في مرض الحزاز المنبسط تأثير مصاحبة الفيروس الكبدي "سي"
المؤلفون المشاركون
Ahmad, Suhayr Muhammad
Mubashir, Ala al-Din Abd al-Al
Mahmud, Ahmad Muhammad
المصدر
العدد
المجلد 26، العدد 3 (31 يوليو/تموز 2002)، ص ص. 35-42، 8ص.
الناشر
تاريخ النشر
2002-07-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Immunological mechanisms have been suggested to be fundamental in the initiation and perpetuation of lichen planus (LP).
Adhesion molecules such as ICAM-1, VCAM-I and E-selectin, play an important role in immune cell interaction.
LP has recently been observed to occur with increased frequency in patients with hepatitis C virus.
So the aim of this work is to measure serum levels of ICAM-1, VCAM-I and E-selectin in LP patients and to compare the levels of these adhesion molecules in LP patients associated with and without HCV.
Serum levels of slCAM-1, sVCAM-1 andsE-selectin were measured by ELISA in 48 LP patients (38 classic and 10 actinic) and 24 healthy controls.
Both patients and controls were screened for hepatitis C virus antibodies by ELISA technique.
Serum levels of sICAM-1, sVCAM-1 and sE-selectin were significantly higher in LP patients compared to controls (P< 0.05, 0.01 and 0.001 respectively).
Only sE-selectin was significantly higher in actinic patients compared to patients with classical LP(P< 0.05).
There were no significant difference in the studied parameters between patients with and without mucus membrane affection.
Hepatitis C associated LP patients (15=31%) had significantly higher levels of sICAM-1 and sVCAM-1 compared to hepatitis C negative patients (P < 0.001 and 0.05 respectively).
No significant difference in the levels ofsE-selectin was found between the two groups.
Adhesion molecules, may play an important role in the pathogenesis of lichen planus, with a distinct role of hepatitis C virus on ICAM-l.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mubashir, Ala al-Din Abd al-Al& Ahmad, Suhayr Muhammad& Mahmud, Ahmad Muhammad. 2002. Serum levels of adhesion molecules in lichen planus and the effect of associated hepatitis C virus. Assiut Medical Journal،Vol. 26, no. 3, pp.35-42.
https://search.emarefa.net/detail/BIM-56541
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ahmad, Suhayr Muhammad…[et al.]. Serum levels of adhesion molecules in lichen planus and the effect of associated hepatitis C virus. Assiut Medical Journal Vol.26, No.3(July, 2002), pp.35-42.
https://search.emarefa.net/detail/BIM-56541
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mubashir, Ala al-Din Abd al-Al& Ahmad, Suhayr Muhammad& Mahmud, Ahmad Muhammad. Serum levels of adhesion molecules in lichen planus and the effect of associated hepatitis C virus. Assiut Medical Journal. 2002. Vol. 26, no. 3, pp.35-42.
https://search.emarefa.net/detail/BIM-56541
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 42
رقم السجل
BIM-56541
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر