The role of interleukine-33 in inflammatory bowel disease
المؤلفون المشاركون
Hwaydi, Raghad R.
al-Khazraji, Khalid A. Jasim
Abbas, Ahmad A.
المصدر
al-Kindy College Medical Journal
العدد
المجلد 10، العدد 2 (31 ديسمبر/كانون الأول 2014)، ص ص. 14-18، 5ص.
الناشر
تاريخ النشر
2014-12-31
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : The inflammatory bowel disease (IBD), Crohn’s disease (CD) and ulcerative colitis (UC) are heterogenous chronic inflammatory disorders of the gastrointestinal tract.
The most widely accepted etiopathogenic hypothesis for these disorders suggests an immune mediated process.
Objective : This study was performed to evaluate the role of interleukine-33 in pathogenesis of inflammatory bowel disease and to correlate their levels with the disease activity and/or severity.
Methods : Fifty five subjects with inflammatory bowel disease (41 ulcerative colitis patients and 14 Crohn’s disease patients) their ages range from 16-65 years and 25 apparently healthy volunteers their ages and sexes were matched with the patients were participated in this study.
Blood samples were collected from all patients and controls to assess serum concentrations of interleukine-33 by enzyme-linked immune-sorbent assay.
Results : The present data revealed that there was significant elevation (P < 0.
05) in serum levels of interleukine-33 in ulcerative colitis and Crohn’s disease patients as compared with control group.
Concerning the correlation between serum levels of interleukine-33 with clinical parameters, the current study revealed a positive correlation between serum interleukine-33 with the disease activity in ulcerative colitis (P = 0.
41).
As regards to disease location, interleukine-33 was significantly higher (P < 0.
001) in ulcerative colitis patients with pan-colitis (E3) as compared to those patients with proctitis disease (E1) and CD of the colon (E2).
Conclusion : This study indicated that interleukine-33 might be a crucial mediator in the pathogenesis of inflammatory bowel disease
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hwaydi, Raghad R.& Abbas, Ahmad A.& al-Khazraji, Khalid A. Jasim. 2014. The role of interleukine-33 in inflammatory bowel disease. al-Kindy College Medical Journal،Vol. 10, no. 2, pp.14-18.
https://search.emarefa.net/detail/BIM-580734
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hwaydi, Raghad R.…[et al.]. The role of interleukine-33 in inflammatory bowel disease. al-Kindy College Medical Journal Vol. 10, no. 2 (2014), pp.14-18.
https://search.emarefa.net/detail/BIM-580734
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hwaydi, Raghad R.& Abbas, Ahmad A.& al-Khazraji, Khalid A. Jasim. The role of interleukine-33 in inflammatory bowel disease. al-Kindy College Medical Journal. 2014. Vol. 10, no. 2, pp.14-18.
https://search.emarefa.net/detail/BIM-580734
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 18
رقم السجل
BIM-580734
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر