Serum levels of ghrelin, adipokines, and tumor necrosis factor-a (Tnf-a) in patients with juvenile idiopathic arthritis in Assuit University Hospitals : relation to nutritional status and disease activity
المؤلفون المشاركون
Salim, Zahra I.
Monzea, Iman M. M.
Sharif, Tahra Muhammad Kamil Sad al-Din
Abd al-Aziz, Nafisah H. R.
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 63، العدد 2 (30 يونيو/حزيران 2015)، ص ص. 52-57، 6ص.
الناشر
تاريخ النشر
2015-06-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: In juvenile idiopathic arthritis (JIA) several proinflammatory cytokines are secreted leading to anorexia and weight loss.
Objectives: We aimed to measure serum levels of ghrelin, adipocytokines and tumor necrosis factor alpha (TNF-a) in JIA patients.
Also, to correlate them with disease activity and patients’ body mass index (BMI).
Patients and methods: Sixty-five patients with JIA (40 girls and 25 boys; means ±SD of age were 12.1 ±3.5 years) and 54 matched healthy controls were evaluated by ELISA to measure levels of ghrelin, leptin, adiponectin and TNF-a and correlate these levels with Juvenile Arthritis Disease Activity Score (JADAS) and patients’ BMI.
Results: Thirty-four patients (52.3%) had active disease while 31 (47.7%) had inactive disease.
JIA patients had significantly lower level of ghrelin and leptin and significantly higher level of TNF-a than the control group (P 6 0.001, P 6 0.05, P 6 0.001, respectively).
Those with active disease had significantly lower level of ghrelin and significantly higher TNF-a level than those with inactive disease (P 6 0.001, P 6 0.01, respectively).
Significant positive correlations were
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salim, Zahra I.& Abd al-Aziz, Nafisah H. R.& Sharif, Tahra Muhammad Kamil Sad al-Din& Monzea, Iman M. M.. 2015. Serum levels of ghrelin, adipokines, and tumor necrosis factor-a (Tnf-a) in patients with juvenile idiopathic arthritis in Assuit University Hospitals : relation to nutritional status and disease activity. Egyptian Pediatric Association Gazette،Vol. 63, no. 2, pp.52-57.
https://search.emarefa.net/detail/BIM-591933
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salim, Zahra I.…[et al.]. Serum levels of ghrelin, adipokines, and tumor necrosis factor-a (Tnf-a) in patients with juvenile idiopathic arthritis in Assuit University Hospitals : relation to nutritional status and disease activity. Egyptian Pediatric Association Gazette Vol. 63, no. 2 (Jun. 2015), pp.52-57.
https://search.emarefa.net/detail/BIM-591933
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salim, Zahra I.& Abd al-Aziz, Nafisah H. R.& Sharif, Tahra Muhammad Kamil Sad al-Din& Monzea, Iman M. M.. Serum levels of ghrelin, adipokines, and tumor necrosis factor-a (Tnf-a) in patients with juvenile idiopathic arthritis in Assuit University Hospitals : relation to nutritional status and disease activity. Egyptian Pediatric Association Gazette. 2015. Vol. 63, no. 2, pp.52-57.
https://search.emarefa.net/detail/BIM-591933
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 56-57
رقم السجل
BIM-591933
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر