Evaluation of three plant extracts activity to the stopping of bleeding in albino mice

العناوين الأخرى

تقييم فاعلية ثلاث مستخلصات نباتية في إيقاف نزيف الدم في الفئران البيض

مقدم أطروحة جامعية

al-Naqqash, Zahra Abd al-Ilah Muhammad Ali

مشرف أطروحة جامعية

al-Shahwani, Iyad Wajih Rauf
Jawad, Abd al-Latif Muhammad

أعضاء اللجنة

Muhsin, Salah Mahdi
Jasim, Abd al-Karim
al-Alujy, Sabah Nasir

الجامعة

جامعة بغداد

الكلية

كلية العلوم

القسم الأكاديمي

قسم علوم الحياة

دولة الجامعة

العراق

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2013

الملخص الإنجليزي

This study included the identification of extracted crude alkaloids, phenols and terpenes compounds from dry rhizomes of Zingiber officinale Roscoe, dry leaves of Thymus vulgaris L.

and dry gum of Acacia arabica L.

Evaluation of their activity as a coagulant factor through observing the changes occurred on bleeding time, clotting time and platelets count in mice under study were determined.

Results showed that alkaloids yielded from Z.

officinale dry rhizomes extract were the highest weight percentage; while terpens extracted from T.

vulgaris dry leaves were the highest yield percentage.

However phenols extracted from A.

arabica dry gum were the highest.

In this study seventy five male lab mice from balb-c breed with average body weight of (28±2) gm were divided randomly into twenty five groups treated with three concentrations (1mg/ml, 5mg/ml, 10 mg/ml) for each plant extract with a single dose (0.4ml) once a day for seven days successively.

Then the mice undergone bleeding time, clotting time and platelets count tests to observe the changes made by the given extracts.

In general the results showed significant differences at (P<0.05) in the parameters of the test; bleeding time and clotting time were decreased significantly compared with the control while platelets count increased significantly compared with control.

Crude alkaloids extract of Z.

officinale was most effective at (10 mg/ml) concentration comparing with other compounds.

While crude terpens extract of T.

vulgaris dry leaves was the most effective at (10 mg/ml) with a slight difference followed by crude terpenes extract of Z.

officinale dry rhizomes at (10 mg/ml).

However crude phenols extract of A.

arabica dry gum was the most effective at (1 mg/ml) on the tested parameters compared with the control and also in comparison with plants under study because results showed higher yield percentage and the most effective concentration was 1mg\ml which make crude phenols extract of A.

arabica the best plant product pharmaceutically and commercially.

التخصصات الرئيسية

الأحياء

الموضوعات

• النباتات الطبية
• الدم

عدد الصفحات

106

قائمة المحتويات

• APA
• MLA
• AMA

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-598285