Evaluation of three plant extracts activity to the stopping of bleeding in albino mice
Other Title(s)
تقييم فاعلية ثلاث مستخلصات نباتية في إيقاف نزيف الدم في الفئران البيض
Dissertant
al-Naqqash, Zahra Abd al-Ilah Muhammad Ali
Thesis advisor
al-Shahwani, Iyad Wajih Rauf
Jawad, Abd al-Latif Muhammad
Comitee Members
Muhsin, Salah Mahdi
Jasim, Abd al-Karim
al-Alujy, Sabah Nasir
University
University of Baghdad
Faculty
College of Science
Department
Department of Biology
University Country
Iraq
Degree
Master
Degree Date
2013
English Abstract
This study included the identification of extracted crude alkaloids, phenols and terpenes compounds from dry rhizomes of Zingiber officinale Roscoe, dry leaves of Thymus vulgaris L.
and dry gum of Acacia arabica L.
Evaluation of their activity as a coagulant factor through observing the changes occurred on bleeding time, clotting time and platelets count in mice under study were determined.
Results showed that alkaloids yielded from Z.
officinale dry rhizomes extract were the highest weight percentage; while terpens extracted from T.
vulgaris dry leaves were the highest yield percentage.
However phenols extracted from A.
arabica dry gum were the highest.
In this study seventy five male lab mice from balb-c breed with average body weight of (28±2) gm were divided randomly into twenty five groups treated with three concentrations (1mg/ml, 5mg/ml, 10 mg/ml) for each plant extract with a single dose (0.4ml) once a day for seven days successively.
Then the mice undergone bleeding time, clotting time and platelets count tests to observe the changes made by the given extracts.
In general the results showed significant differences at (P<0.05) in the parameters of the test; bleeding time and clotting time were decreased significantly compared with the control while platelets count increased significantly compared with control.
Crude alkaloids extract of Z.
officinale was most effective at (10 mg/ml) concentration comparing with other compounds.
While crude terpens extract of T.
vulgaris dry leaves was the most effective at (10 mg/ml) with a slight difference followed by crude terpenes extract of Z.
officinale dry rhizomes at (10 mg/ml).
However crude phenols extract of A.
arabica dry gum was the most effective at (1 mg/ml) on the tested parameters compared with the control and also in comparison with plants under study because results showed higher yield percentage and the most effective concentration was 1mg\ml which make crude phenols extract of A.
arabica the best plant product pharmaceutically and commercially.
Main Subjects
Topics
No. of Pages
106
Table of Contents
Table of contents.
Abstract.
Abstract in Arabic.
Chapter One : Introduction and literature review.
Chapter Two : Materials and methods.
Chapter Three : Results.
Chapter Four : Discussion.
Conclusions and recommendations.
References.
American Psychological Association (APA)
al-Naqqash, Zahra Abd al-Ilah Muhammad Ali. (2013). Evaluation of three plant extracts activity to the stopping of bleeding in albino mice. (Master's theses Theses and Dissertations Master). University of Baghdad, Iraq
https://search.emarefa.net/detail/BIM-598285
Modern Language Association (MLA)
al-Naqqash, Zahra Abd al-Ilah Muhammad Ali. Evaluation of three plant extracts activity to the stopping of bleeding in albino mice. (Master's theses Theses and Dissertations Master). University of Baghdad. (2013).
https://search.emarefa.net/detail/BIM-598285
American Medical Association (AMA)
al-Naqqash, Zahra Abd al-Ilah Muhammad Ali. (2013). Evaluation of three plant extracts activity to the stopping of bleeding in albino mice. (Master's theses Theses and Dissertations Master). University of Baghdad, Iraq
https://search.emarefa.net/detail/BIM-598285
Language
English
Data Type
Arab Theses
Record ID
BIM-598285
