![](/images/graphics-bg.png)
Low dose tadalafil effect on anthropometric and metabolic parameters in Iraqi diabetic obese men
المؤلف
المصدر
al-Kindy College Medical Journal
العدد
المجلد 10، العدد 2 (31 ديسمبر/كانون الأول 2014)، ص ص. 91-95، 5ص.
الناشر
تاريخ النشر
2014-12-31
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background: Phosphodiesterase-5 (PDE-5) inhibitors restore nitric oxide (NO) signaling and may reduce circulating inflammatory markers, and improve metabolic parameters through a number of mechanisms.
Daily administration of the PDE-5 inhibitor, tadalafil (TAD) may attenuate inflammation; improve fasting plasma glucose and triglyceride levels and body weight.
This study aims to evaluate the efficacy of low dose PDE-5 inhibitor, tadalafil (TAD) in controlling dysglycemia and body weight in obese diabetic men.
Methods: Forty obese men with type 2 diabetes aged 30-50 years incorporated in this study, all with A1c of 7-8.5%, attending obesity unit in AL-Kindy college of medicine.
Weight, height, BMI, FPG, A1c, cholesterol, TG, HDL and LDL measured for all and advised for low calories diet and increasing exercise and randomized into 2 groups , first (control) without and the second (therapy) with addition of tadalafil 2.5mg/day for 8 weeks, then remeasure all the parameters after.
Results blotted in tables and statistical analysis done using SPSS program and t-test.
Results: There was significant reduction in weight, BMI, FPG, cholesterol, TG and LDL, while no significant change in A1c , and although there was elevation in HDL but was insignificant in control group.
In therapy group both weight, BMI, FPG, A1c, cholesterol, TG, and LDL show significant reduction, with mild insignificant elevation in HD.
When compare the results of both groups significant results appear in percentage of change of FPG and A1c in therapy group.
Conclusion: Low calories diet and exercise are effective in reducing obesity parameters in type 2 diabetes, in addition, improve dysglycemia and dyslipidemia , adding tadalafil 2.5mg/day can add beneficial effect specifically for FPG and A1c significantly
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khazal, Faris A.. 2014. Low dose tadalafil effect on anthropometric and metabolic parameters in Iraqi diabetic obese men. al-Kindy College Medical Journal،Vol. 10, no. 2, pp.91-95.
https://search.emarefa.net/detail/BIM-624939
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khazal, Faris A.. Low dose tadalafil effect on anthropometric and metabolic parameters in Iraqi diabetic obese men. al-Kindy College Medical Journal Vol. 10, no. 2 (2014), pp.91-95.
https://search.emarefa.net/detail/BIM-624939
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khazal, Faris A.. Low dose tadalafil effect on anthropometric and metabolic parameters in Iraqi diabetic obese men. al-Kindy College Medical Journal. 2014. Vol. 10, no. 2, pp.91-95.
https://search.emarefa.net/detail/BIM-624939
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 94-95
رقم السجل
BIM-624939
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)