Association between polycystic ovary syndrome and genetic polymorphisms of CYP 17 gene in Iraqi women
المؤلفون المشاركون
Muhammad, Marwah B.
Umran, Mahfuzah A.
al-Awadi, Salwa Jabir Abd Allah
المصدر
Iraqi Journal of Biotechnology
العدد
المجلد 14، العدد 2 (31 ديسمبر/كانون الأول 2015)، ص ص. 99-110، 12ص.
الناشر
جامعة بغداد معهد الهندسة الوراثية و التقنيات الإحيائية للدراسات العليا
تاريخ النشر
2015-12-31
دولة النشر
العراق
عدد الصفحات
12
التخصصات الرئيسية
الموضوعات
الملخص EN
Polycystic ovary syndrome (PCOS), whose genetic basis is not completely well understood, it is the most common endocrine disorder in women in their reproductive years.
Blood samples were col-lected from two groups.
The first group included 61 females with PCOS and the second group included 30 normal females to detect the presence of mutation in the CYP17 gene.
The two groups were genotyped and a comparison was done between them.
The results showed a significant difference (p<0.05) in FSH levels in patients and normal females and there is no significant difference in the levels of Testosterone, prolactin and LH.
Moreover, it showed a significant difference (p<0.05) in the levels of HDL in both pa-tients and normal females and no significant difference in the levels of (LDL, VLDL, Triglyceride and cholesterol).
Two comparisons for genotype were done: one between age and genotype and the second between BMI and genotype for each group.
The results showed two types of genotype, which were a TT wild type and a heterozygote TC mutant type.
Furthermore, the results showed a significant difference (p<0.05) in genotype TT and TC in the group of age less than 25 years old and no significant difference in these genotypes in age groups (25-35) and those with more than 35 years old.
It is concluded from this study that this single nucleotide polymorphism in the CYP 17 gene was not associated with PCOS in Iraqi women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muhammad, Marwah B.& al-Awadi, Salwa Jabir Abd Allah& Umran, Mahfuzah A.. 2015. Association between polycystic ovary syndrome and genetic polymorphisms of CYP 17 gene in Iraqi women. Iraqi Journal of Biotechnology،Vol. 14, no. 2, pp.99-110.
https://search.emarefa.net/detail/BIM-644807
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Muhammad, Marwah B.…[et al.]. Association between polycystic ovary syndrome and genetic polymorphisms of CYP 17 gene in Iraqi women. Iraqi Journal of Biotechnology Vol. 14, no. 2 (2015), pp.99-110.
https://search.emarefa.net/detail/BIM-644807
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muhammad, Marwah B.& al-Awadi, Salwa Jabir Abd Allah& Umran, Mahfuzah A.. Association between polycystic ovary syndrome and genetic polymorphisms of CYP 17 gene in Iraqi women. Iraqi Journal of Biotechnology. 2015. Vol. 14, no. 2, pp.99-110.
https://search.emarefa.net/detail/BIM-644807
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 108-110
رقم السجل
BIM-644807
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر