Topical application of tranexamic acid versus systemic injection during coronary artery bypass graft surgery : a comparative study
المؤلفون المشاركون
Kamali, Ayman M.
Siyam, Ilham A.
al-Nahas, Yasir M.
Abd al-Aziz, Abd al-Aziz A.
Masud, Amr M.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 8، العدد 4 (31 ديسمبر/كانون الأول 2015)، ص ص. 479-482، 4ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2015-12-31
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Diffuse microvascular bleeding remains a common problem after myocardial revascularization with cardiopulmonary bypass.
Objectives The effi cacy of locally administered tranexamic acid (topical application) was compared with systemically administered tranexamic acid to reduce postoperative bleeding after cardiopulmonary bypass in elective nonredo coronary artery bypass grafting ( CABG).
Methods The study included 60 patients of both sexes, aged between 35 and 65 years, and scheduled for elective CABG; patients were randomly assigned to two groups: group I (the intravenous tranexamic acid group; 30 patients) and group II (the topical tranexamic acid group; 30 patients).
For each patient in each group, postoperative blood loss, number of units of packed red blood cells (RBCs) and fresh frozen plasma ( FFP) transfused, frequency of resternotomy, duration of hospital and ICU stay, and mortality were recorded.
Results There were statistically signifi cant differences between the two groups with regard to total postoperative blood loss and need for packed RBCs and FFP transfusion, being much greater in group I than in group II.
There was no mortality in either group.
Frequency of resternotomy was higher in group I than in group II, although the difference was statistically nonsignifi cant.
The duration of hospital and ICU stay revealed no statistically signifi cant differences between the two groups.
Conclusion Intraoperative topical administration of tanexamic acid into the pericardial cavity before sternal closure during CABG surgery has reduced the incidence of postoperative blood loss and the need for postoperative packed RBCs and FFP transfusion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Siyam, Ilham A.& Kamali, Ayman M.& al-Nahas, Yasir M.& Abd al-Aziz, Abd al-Aziz A.& Masud, Amr M.. 2015. Topical application of tranexamic acid versus systemic injection during coronary artery bypass graft surgery : a comparative study. Ain Shams Journal of Anesthesiology،Vol. 8, no. 4, pp.479-482.
https://search.emarefa.net/detail/BIM-655164
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Siyam, Ilham A.…[et al.]. Topical application of tranexamic acid versus systemic injection during coronary artery bypass graft surgery : a comparative study. Ain Shams Journal of Anesthesiology Vol. 8, no. 4 (Oct. / Dec. 2015), pp.479-482.
https://search.emarefa.net/detail/BIM-655164
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Siyam, Ilham A.& Kamali, Ayman M.& al-Nahas, Yasir M.& Abd al-Aziz, Abd al-Aziz A.& Masud, Amr M.. Topical application of tranexamic acid versus systemic injection during coronary artery bypass graft surgery : a comparative study. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 4, pp.479-482.
https://search.emarefa.net/detail/BIM-655164
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 482
رقم السجل
BIM-655164
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر