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Does intrathecal midazolam improve hyperbaric bupivacaine-fentanyl anesthesia in elderly patients ?
المؤلفون المشاركون
Boules, Majid L.
Ubayd, Riham S.
Ali, Muhammad Z.
Samhan, Yasir M.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 8، العدد 4 (31 ديسمبر/كانون الأول 2015)، ص ص. 602-607، 6ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2015-12-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective To assess the effect of intrathecal midazolam with bupivacaine–fentanyl in elderly patients undergoing endourologic procedures.
Materials and methods This prospective, randomized, double-blind study involved 60 ASA physical status II-III patients aged over 60 years scheduled for elective endoscopic urologic procedures under spinal anesthesia with hyperbaric bupivacaine 0.5% (5 mg/ml).
They were randomized into one of three equal groups of 20 patients each: the fi rst group, control group (group C), received 7.5 mg hyperbaric bupivacaine 0.5% in a volume of 1.5 ml; the second group, fentanyl group (group F), received 7.5 mg hyperbaric bupivacaine 0.5% in a volume of 1.5 ml and 10 μg fentanyl (0.1 ml); and the third group, fentanylmidazolam group (group FM), received 7.5 mg hyperbaric bupivacaine 0.5% in a volume of 1.5 ml and 10 μg fentanyl (0.1 ml) plus 1.0 mg of midazolam (0.2 ml).
Sensory and motor effects were assessed.
Postoperative pain, sedation, and adverse effects were also recorded.
Results The three studied groups were comparable in demographic and clinical characteristics.
They were hemodynamically stable.
There was no signifi cant difference between the three groups in the onset of sensory (P = 0.721) and motor block (P = 0.342), duration of motor block (P = 0.286), and sedation score (P = 0.229).
Duration of sensory block was prolonged in group F compared with the control group (P < 0.001) and prolonged more in group FM compared with the F group (P = 0.065).
Time to fi rst request of rescue analgesic was signifi cantly longer in group F compared with the C group (P = 0.033) and in FM compared with the F group (P < 0.001).
All patients reported excellent or good degree of satisfaction with anesthetic procedure (P = 0.547).
Conclusion Adjuvant intrathecal midazolam resulted in intraoperative hemodynamic stability and safely potentiates postoperative analgesic effect of bupivacainefentanyl spinal anesthesia in elderly patients undergoing endourologic procedures.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ubayd, Riham S.& Ali, Muhammad Z.& Boules, Majid L.& Samhan, Yasir M.. 2015. Does intrathecal midazolam improve hyperbaric bupivacaine-fentanyl anesthesia in elderly patients ?. Ain Shams Journal of Anesthesiology،Vol. 8, no. 4, pp.602-607.
https://search.emarefa.net/detail/BIM-655286
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ubayd, Riham S.…[et al.]. Does intrathecal midazolam improve hyperbaric bupivacaine-fentanyl anesthesia in elderly patients ?. Ain Shams Journal of Anesthesiology Vol. 8, no. 4 (Oct. / Dec. 2015), pp.602-607.
https://search.emarefa.net/detail/BIM-655286
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ubayd, Riham S.& Ali, Muhammad Z.& Boules, Majid L.& Samhan, Yasir M.. Does intrathecal midazolam improve hyperbaric bupivacaine-fentanyl anesthesia in elderly patients ?. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 4, pp.602-607.
https://search.emarefa.net/detail/BIM-655286
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 606-607
رقم السجل
BIM-655286
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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