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Comparative study between the effect of stem cells and Metacam on induced arthritis in dogs
العناوين الأخرى
دراسة مقارنة بين تأثير علاج الخلايا الجذعية و دواء الميتاكم على التهاب المفاصل المستحدث في الكلاب
المؤلف
المصدر
Kufa Journal for Veterinary Medical Sciences
العدد
المجلد 6، العدد 1 (30 يونيو/حزيران 2015)، ص ص. 85-96، 12ص.
الناشر
جامعة الكوفة كلية الطب البيطري
تاريخ النشر
2015-06-30
دولة النشر
العراق
عدد الصفحات
12
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective of this project was to study the effect of stem cells on the induced arthritis in the dogs as compared with treatment Metacam®.
Incomplete fruend's adjuvant was used to induce arthritis.
Twenty five dogs aged 12 month were divided into five groups: 1st group (T1) was negative control, while 2nd group (T2) was induced without any treatment (positive control), 3rd group (T3) was induction arthritis and treated with 0.2 mg/kg B.W.
of Metacam® intravenously (I/V) injection, 4th group (T4) was induced and treated with 1ml/kg of B.W of suspension of culture media injected (I / V), and 5th group (T5) was treated with stem cells suspension in a dose of 2.5 x 106 cells / ml / Kg B.W.
(I/V) injection.
Typical clinical signs of arthritis appeared on all induction groups.
The results of Hb and RBCs showed clear reduction in all induction groups as compared with (T1), the WBCs, Erythrocyte sediment rates (ESR) and C- reactive protein (CRP) in (T2) showed clear elevation as compared with (T1), After 15 and 30 days of treatment the RBCs count and HB level showed significant decline in T2, T3 and T4 as compared with T5 and T1, the WBCs ,ESR and CRP significantly elevated in the T2 and T4 as compared with T1.
The T3 and T5 showed clear depletion in levels of WBCs, ESR and CRP as compared with T2 after 15 and 30 days of treatment, while the T5 revealed no significant difference as compared with T1 after 30 days of treatment.
The histopathological changes in T2 and T4 showed erosion and infiltration of inflammatory cells, T3 showed hypertrophy of synovial lining and mild inflammatory cells in synovium, T5 explained return the bone tissue to normal.
In this experiment concluded a successful use of stem cells in treatment of arthritis without side effect as comparison with Metacam
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luibi, Adi Karim. 2015. Comparative study between the effect of stem cells and Metacam on induced arthritis in dogs. Kufa Journal for Veterinary Medical Sciences،Vol. 6, no. 1, pp.85-96.
https://search.emarefa.net/detail/BIM-655854
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luibi, Adi Karim. Comparative study between the effect of stem cells and Metacam on induced arthritis in dogs. Kufa Journal for Veterinary Medical Sciences Vol. 6, no. 1 (Jun. 2015), pp.85-96.
https://search.emarefa.net/detail/BIM-655854
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luibi, Adi Karim. Comparative study between the effect of stem cells and Metacam on induced arthritis in dogs. Kufa Journal for Veterinary Medical Sciences. 2015. Vol. 6, no. 1, pp.85-96.
https://search.emarefa.net/detail/BIM-655854
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 94-96
رقم السجل
BIM-655854
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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