Non-invasive predictors of portal hypertension in patients with hepatitis C virus related hepatocellular carcinoma
المؤلفون المشاركون
Mahran, Zakariyya Y.
Saqr, Muhammad
al-Baz, Ahmad
Barakat, Iman
Abu al-Muti, Muhammad
Abd al-Hamid, Muhammad
المصدر
Journal of the Egyptian Society of Parasitology
العدد
المجلد 45، العدد 3 (31 ديسمبر/كانون الأول 2015)، ص ص. 545-554، 10ص.
الناشر
الجمعية المصرية لعلم الطفيليات
تاريخ النشر
2015-12-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
The reference standard for portal venous pressure measurement which is clinically important for estimating the feasibility of resection of hepatocellular carcinoma is the hepatic venous pressure gradient, which is invasive and expensive.
The present study evaluated the noninvasive parameters for assessment of portal hypertension in Child A patients with hepatocellular carcinoma on top of hepatitis C virus.
A total of 112 patients were subjected to clinical assessment, biochemical assay, ultrasonographic Doppler study, triphasic spiral abdominal computed tomography, upper gastrointestinal endoscopy and hepatic venous pressure gradient measurement.
According to hepatic venous pressure gradient measurement, they were classified into groups: GI: 58 patients with hepatic venous pressure gradient <10 mmHg and GII: 54 patients with hepatic venous pressure gradient ≥ 10 mmHg.
Significant variables in univariate analysis were included in a multivariate analysis to establish a model for prediction of clinically significant portal hypertension.
Results showed that portal vein diameter ≥ 1.3 cm, mono or biphasic pattern of flow in hepatic veins and Giannini index ≤ 909 were independent risk factors for the clinically significant portal hypertension as indicated by HVPG ≥ 10 mmHg.
A model with highest likelihood ratio and good fitness was created.
This prediction model was displayed by the receiver operating characteristic curve and under the curve area was 0.969 (0.938-1).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mahran, Zakariyya Y.& Saqr, Muhammad& Barakat, Iman& al-Baz, Ahmad& Abd al-Hamid, Muhammad& Abu al-Muti, Muhammad. 2015. Non-invasive predictors of portal hypertension in patients with hepatitis C virus related hepatocellular carcinoma. Journal of the Egyptian Society of Parasitology،Vol. 45, no. 3, pp.545-554.
https://search.emarefa.net/detail/BIM-668959
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mahran, Zakariyya Y.…[et al.]. Non-invasive predictors of portal hypertension in patients with hepatitis C virus related hepatocellular carcinoma. Journal of the Egyptian Society of Parasitology Vol. 45, no. 3 (Dec. 2015), pp.545-554.
https://search.emarefa.net/detail/BIM-668959
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mahran, Zakariyya Y.& Saqr, Muhammad& Barakat, Iman& al-Baz, Ahmad& Abd al-Hamid, Muhammad& Abu al-Muti, Muhammad. Non-invasive predictors of portal hypertension in patients with hepatitis C virus related hepatocellular carcinoma. Journal of the Egyptian Society of Parasitology. 2015. Vol. 45, no. 3, pp.545-554.
https://search.emarefa.net/detail/BIM-668959
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 552-554
رقم السجل
BIM-668959
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر