Interleukine-6 level in saliva of patients with chronic Periodontitis : a case-control study
المؤلف
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 28، العدد 1 (31 مارس/آذار 2016)، ص ص. 103-108، 6ص.
الناشر
تاريخ النشر
2016-03-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background:Periodontal diseases are infectious diseases in which periodontalpathogens trigger chronic inflammatory and immune responses.
Interleukine-6 is a multifunctional cytokine playing a central role in inflammation and tissue injury.The aim of the study IS to determine the level of Interleukin-6(IL-6) in saliva of patients with chronic periodontitis compared to healthy subjects.
Materials and Methods:The total subjects of the present study is 60, divided into 3 groups; 20 patients with chronic periodontitis with pocket depth(PD ≥4 mm)(group I), 20 patients with pocket depth(PD <4 mm) with clinical attachment loss (group II), and 20 healthy controls with pocket probing depth (PPD ≤ 3 mm) without clinical attachment loss (group III).
Un-stimulated salivary sample was taken from each subject and was investigated for the presence of Interleukine-6by using Enzyme‑linked Immunosorbent Assay (ELISA) technology.
Results:Mean IL-6 levels in saliva in patients with chronic periodontitis (98.40 ± 18.44 ng/L)was significantly higher than in controls (11.67 ± 3.32; p=0.001).
Also a significant difference in IL-6 levels in saliva was observed between the PPD ≥ 4 mm and PPD < 4 mm groups and between PPD ≥ 4 mm and control groups, as well as statistically significant differences were observed between PPD < 4 mm and control groups (P < 0.001).
Conclusion:The Interleukine-6 level in saliva can be considered as one of inflammatory biomarker indicators of severity of periodontitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nanakaly, Haween T.. 2016. Interleukine-6 level in saliva of patients with chronic Periodontitis : a case-control study. Journal of Baghdad College of Dentistry،Vol. 28, no. 1, pp.103-108.
https://search.emarefa.net/detail/BIM-683418
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nanakaly, Haween T.. Interleukine-6 level in saliva of patients with chronic Periodontitis : a case-control study. Journal of Baghdad College of Dentistry Vol. 28, no. 1 (Mar. 2016), pp.103-108.
https://search.emarefa.net/detail/BIM-683418
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nanakaly, Haween T.. Interleukine-6 level in saliva of patients with chronic Periodontitis : a case-control study. Journal of Baghdad College of Dentistry. 2016. Vol. 28, no. 1, pp.103-108.
https://search.emarefa.net/detail/BIM-683418
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 107-108
رقم السجل
BIM-683418
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر