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The relationship between concentrations of magnesium and oxidized low-density lipoprotein and beta2-microglobulin in the serum of patients on the end-stage of renal disease
المؤلفون المشاركون
Raikou, Vaia D.
Kyriaki, Despina
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 27، العدد 3 (30 يونيو/حزيران 2016)، ص ص. 546-552، 7ص.
الناشر
تاريخ النشر
2016-06-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
The end-stage of renal disease is associated with increased oxidative stress and oxidative modification of low-density lipoproteins (LDLs).
Beta2 microglobulin (beta2M) is accumulated in the serum of dialysis patients.
Magnesium (Mg) plays a protective role in the development of oxidative stress in healthy subjects.
We studied the relationship between concentrations of magnesium and oxidized LDL (ox-LDL) and beta2M in the serum of patients on the end stage of renal disease.
In 96 patients on on-line- predilution hemodiafiltration, beta2M and intact parathormone were measured by radioimmunoassays.
High-sensitivity C-reactive protein (hsCRP) and ox-LDL were measured using ΕLISA.
Serum bicarbonate levels were measured in the blood gas analyser gas machine.
We performed logistic regression analysis models to investigate Mg as an important independent predictor of elevated ox-LDL and high beta2M serum concentrations, after adjustment to traditional and specific for dialysis patients’ factors.
We observed a positive correlation of Mg with ox-LDL (r = 0.383, P = 0.001), but the association of Mg with beta2M, hsCRP, and serum bicarbonate levels was significantly inverse (r = −0.252, P = 0.01, r = −0.292, P = 0.004, and r = −0.282, P = 0.04 respectively).
The built logistic-regression analysis showed that Mg act as a significant independent factor for the elevated ox-LDL and beta2M serum concentrations adjusting to traditional and specific factors for these patients.
We observed a positive relationship between magnesium and acidosis statusrelated ox-LDL concentrations, but the inverse association between magnesium and beta2M serum concentrations in hemodialysis patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Raikou, Vaia D.& Kyriaki, Despina. 2016. The relationship between concentrations of magnesium and oxidized low-density lipoprotein and beta2-microglobulin in the serum of patients on the end-stage of renal disease. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 3, pp.546-552.
https://search.emarefa.net/detail/BIM-683642
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Raikou, Vaia D.& Kyriaki, Despina. The relationship between concentrations of magnesium and oxidized low-density lipoprotein and beta2-microglobulin in the serum of patients on the end-stage of renal disease. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 3 (May. / Jun. 2016), pp.546-552.
https://search.emarefa.net/detail/BIM-683642
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Raikou, Vaia D.& Kyriaki, Despina. The relationship between concentrations of magnesium and oxidized low-density lipoprotein and beta2-microglobulin in the serum of patients on the end-stage of renal disease. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 3, pp.546-552.
https://search.emarefa.net/detail/BIM-683642
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 551-552
رقم السجل
BIM-683642
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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