Study of two-short satiety signals : "cholecystokinin and glucagon-like peptide-1" in obese subjects
المؤلفون المشاركون
al-Banawy, Hisham
Maghazi, Thana Fathi
al-Sahn, Fakarat
al-Sammak, Muhammad
Yasir Ammar Y.
al-Safty, Halah
المصدر
Journal of the Medical Research Institute
العدد
المجلد 27، العدد 3 (30 سبتمبر/أيلول 2006)، ص ص. 177-182، 6ص.
الناشر
جامعة الإسكندرية معهد البحوث الطبية
تاريخ النشر
2006-09-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Feeding behaviour is the result of complex integration of central and peripheral satiety signals.
The latter are either short- or longterm.
This study aimed at evaluation of fasting and half an hour postprandial plasma levels of two of the short-term satiety signals : cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) in obese adults.
Aim of the work: Forty-four non-smoker, non-alcoholic adult subjects of matched age, sex and socioeconomic status were included.
They were grouped as control group of 15 apparently healthy volunteers of ideal body weight and an obese group of 29 non-diabetic obese subjects (BMI>30-40 kg / m2).
Subjects and Methods To all subjects, thorough history was taken, especially as regards dietary habits and physical activity, by special interview questionnaire.
Full physical examination including anthropometric measurements was also done.
Estimation of fasting serum levels of glucose, cholesterol, triglycerides and non-esterified fatty acids as well as plasma CCK and GLP-1 were performed.
After that, all subjects received a test meal followed by calculation of meal size and caloric intake.
After half an hour from the start of meal, postprandial plasma CCK and GLP-1 levels, and two hours postprandial serum glucose were also estimated.
Thereafter, subjects were asked to complete the questionnaire regarding the satiety period and degree of perception of hunger.
Results : From the obtained results, it could be concluded that : (1) Meal enhances the release of CCK and GLP-1.
Such release is correlated with post meal subjective measures of satiety in both studied groups.
Thus, CCK and GLP-1 can be used as biomarkers of satiety.
(2) The meal-related release of CCK and GLP-1 is attenuated in obese group.
Whether such attenuated response is a cause or a consequence of obesity needs further study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maghazi, Thana Fathi& al-Sahn, Fakarat& al-Sammak, Muhammad& Yasir Ammar Y.& al-Banawy, Hisham& al-Safty, Halah. 2006. Study of two-short satiety signals : "cholecystokinin and glucagon-like peptide-1" in obese subjects. Journal of the Medical Research Institute،Vol. 27, no. 3, pp.177-182.
https://search.emarefa.net/detail/BIM-68541
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maghazi, Thana Fathi…[et al.]. Study of two-short satiety signals : "cholecystokinin and glucagon-like peptide-1" in obese subjects. Journal of the Medical Research Institute Vol. 27, no. 3 (2006), pp.177-182.
https://search.emarefa.net/detail/BIM-68541
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maghazi, Thana Fathi& al-Sahn, Fakarat& al-Sammak, Muhammad& Yasir Ammar Y.& al-Banawy, Hisham& al-Safty, Halah. Study of two-short satiety signals : "cholecystokinin and glucagon-like peptide-1" in obese subjects. Journal of the Medical Research Institute. 2006. Vol. 27, no. 3, pp.177-182.
https://search.emarefa.net/detail/BIM-68541
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 81-82
رقم السجل
BIM-68541
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر