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Effect of olea oleaster and juniperus procera leaves extracts on thioacetamide induced hepatic cirrhosis in male albino mice
المؤلفون المشاركون
al-Rabbai, Ali A.
al-Maliki, Dakhl Allah A.
al-Attar, Atif M.
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 23، العدد 3 (31 مايو/أيار 2016)، ص ص. 363-371، 9ص.
الناشر
تاريخ النشر
2016-05-31
دولة النشر
السعودية
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
The effect of Olea oleaster and Juniperus procera leaves extracts and their combination on thioacetamide (TAA)-induced hepatic cirrhosis were investigated in male albino mice.
One hundred sixty mice were used in this study and were randomly distributed into eight groups of 20 each.
Mice of group 1 served as controls.
Mice of group 2 were treated with TAA.
Mice of group 3 were exposed to TAA and supplemented with O.
oleaster leaves extracts.
Mice of group 4 were treated with TAA and supplemented with J.
procera leaves extracts.
Mice of group 5 were subjected to TAA and supplemented with O.
oleaster and J.
procera leaves extracts.
Mice of groups 6, 7 and 8 were supplemented with O.
oleaster, J.
procera, and O.
oleaster and J.
procera leaves extracts respectively.
Administration of TAA for six and twelve weeks resulted in a decline in body weight gain and increased the levels of serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and total bilirubin.
Histopathological evaluations of hepatic sections from mice treated with TAA showed severe alterations including increase of fibrogenesis processes with structural damage.
Treatment of mice with these extracts showed a pronounced attenuation in TAA induced hepatic cirrhosis associated with physiological and histopathological alterations.
Finally, this study suggests that the supplementation of these extracts may act as antioxidant agents and could be an excellent adjuvant support in the therapy of hepatic cirrhosis
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Attar, Atif M.& al-Rabbai, Ali A.& al-Maliki, Dakhl Allah A.. 2016. Effect of olea oleaster and juniperus procera leaves extracts on thioacetamide induced hepatic cirrhosis in male albino mice. Saudi Journal of Biological Sciences،Vol. 23, no. 3, pp.363-371.
https://search.emarefa.net/detail/BIM-689434
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Attar, Atif M.…[et al.]. Effect of olea oleaster and juniperus procera leaves extracts on thioacetamide induced hepatic cirrhosis in male albino mice. Saudi Journal of Biological Sciences Vol. 23, no. 3 (May. 2016), pp.363-371.
https://search.emarefa.net/detail/BIM-689434
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Attar, Atif M.& al-Rabbai, Ali A.& al-Maliki, Dakhl Allah A.. Effect of olea oleaster and juniperus procera leaves extracts on thioacetamide induced hepatic cirrhosis in male albino mice. Saudi Journal of Biological Sciences. 2016. Vol. 23, no. 3, pp.363-371.
https://search.emarefa.net/detail/BIM-689434
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 370-371
رقم السجل
BIM-689434
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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