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Prevalence of merkel cell polyomavirus in Tehran : an age-specific serological study
المؤلفون المشاركون
Vaziri, Mustafa Salihi
Vahabpour, Ruh Allah
Aghasadeghi, Muhammad Rida
Mohajel, Nasir
Nasimi, Maryam
Esghaei, Maryam
Monavari, Seyed Hamidreza
Keyvani, Husayn
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 18، العدد 5 (31 مايو/أيار 2016)، ص ص. 1-7، 7ص.
الناشر
تاريخ النشر
2016-05-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Several new types of polyomavirus have been discovered in recent years mainly because of the recent state-of-the-art detection technologies.
Among the polyomaviruses, Merkel cell polyomavirus (MCPyV) has attracted the most attention because of its possible role in the etiology of Merkel cell carcinoma, a rare but lethal form of skin cancer.
Objectives: This study aimed to determine age-specific seroprevalence of MCPyV in Tehran.
Patients and Methods: In this cross-sectional study, we collected 440 serum samples from healthy individuals 2 to 78 years of age who visited the Pasteur Institute’s clinic in Tehran, Iran, using a convenience sampling strategy.
We developed a virus-like particle-based enzyme-linked immunosorbent assay that uses VP1, the major capsid protein of MCPyV, to detect and quantitate serum antibodies to MCPyV.
We compared the prevalence of MCPyV between males and females and across eight age groups.
Results: A total of 255 (57.9%) of the serum samples were MCPyV positive.
The seroprevalence in children under 10 years of age was 25%.
The seroprevalence increased to 56% over the next decade of life (10 - 19 years of age).
The seroprevalence rate in males and females was 56.1% and 59.7% respectively, and a binary logistic regression showed no significant difference between males and females (P = 0.77).
However, the prevalence of MCPyV increased with age (P = 0.012).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vahabpour, Ruh Allah& Aghasadeghi, Muhammad Rida& Vaziri, Mustafa Salihi& Mohajel, Nasir& Keyvani, Husayn& Nasimi, Maryam…[et al.]. 2016. Prevalence of merkel cell polyomavirus in Tehran : an age-specific serological study. Iranian Red Crescent Medical Journal،Vol. 18, no. 5, pp.1-7.
https://search.emarefa.net/detail/BIM-694763
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vahabpour, Ruh Allah…[et al.]. Prevalence of merkel cell polyomavirus in Tehran : an age-specific serological study. Iranian Red Crescent Medical Journal Vol. 18, no. 5 (May. 2016), pp.1-7.
https://search.emarefa.net/detail/BIM-694763
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vahabpour, Ruh Allah& Aghasadeghi, Muhammad Rida& Vaziri, Mustafa Salihi& Mohajel, Nasir& Keyvani, Husayn& Nasimi, Maryam…[et al.]. Prevalence of merkel cell polyomavirus in Tehran : an age-specific serological study. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 5, pp.1-7.
https://search.emarefa.net/detail/BIM-694763
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6-7
رقم السجل
BIM-694763
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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