Assessment of breast carcinoma by 99mtc-sestamibi scintimammography : effect of lesion site, size and histopathological characteristics
المؤلف
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 12، العدد 3 (30 سبتمبر/أيلول 2000)، ص ص. 183-189، 7ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2000-09-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
This study included 83 female patients with 94 breast lesions.
All patients underwent clinical examination, Xray mammography and 99mTc- MIBI scintimammography (SMM).
Furthermore, fine needle aspiration biopsy (FNAB) was performed for 53 breast lesions prior to surgical excision.
Complete agreement between histopathological diagnosis and SMM was observed in 66 / 80 (82.5 %) malignant lesions, whereas 2 / 14 (14 %) of benign lesions had false positive results and proved to be adenoma and granuloma.
The overall sensitivity, specificity and accuracy were 83 %, 85.5 % and 83 % respectively for SMM and 62.5 %, 59.3 % and 61.4 % for x ray mammography.
This difference was statistically significant (p = 0.006).
On the other had, sensitivity, specificity and accuracy of FNAB was 91.8 %, 90 % and 91 % respectively.
SMM and FNAB did not show much significant difference in their sensitivity, specificity and accuracy (p = 0.318).
The highest diagnostic sensitivity of SMM was 87 % for the detection of invasive carcinoma measuring 1- 2 cm.
However, the sensitivity was only 29 % for the detection of breast lesions less than 1 cm.
On contrast, X-ray mammography had a higher diagnostic sensitivity of 75 % for the detection of malignant breast lesions less than 1 cm.
99mTc-MIBI scintigraphy showed a higher sensitivity of 90 % and 89 % for the diagnosis of breast carcinoma grade 3 and 4 respectively.
While, it had a lower sensitivity of 67 % and 81% for the detection of malignant lesions grade 1 and 2 respectively.
The sensitivity of 99mTc-MIBI scintimammography was not influenced by tumour pathology (invasive ductal carcinoma was 85 % and invasive lobular carcinoma was 80 %) (p = 0.22).
Presence of carcinoma in situ did not affect the diagnostic accuracy of 99mTc- MIBI.
The sensitivity of SMM for the detection of invasive carcinoma with ER + ve was higher than that for the detection of invasive carcinoma with ER-ve (86 % vs 70 % respectively) (p < 0.05).
SMM had a significantly higher sensitivity (95 %) for localizing breast lesions in the retroareolar region compared to that in the other sites (lower inner quadrant 50 %, lower outer 70% and upper inner 82 %).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sabri, Rafat A.. 2000. Assessment of breast carcinoma by 99mtc-sestamibi scintimammography : effect of lesion site, size and histopathological characteristics. Journal of the Egyptian National Cancer Institute،Vol. 12, no. 3, pp.183-189.
https://search.emarefa.net/detail/BIM-69486
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sabri, Rafat A.. Assessment of breast carcinoma by 99mtc-sestamibi scintimammography : effect of lesion site, size and histopathological characteristics. Journal of the Egyptian National Cancer Institute Vol. 12, no. 3 (Sep. 2000), pp.183-189.
https://search.emarefa.net/detail/BIM-69486
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sabri, Rafat A.. Assessment of breast carcinoma by 99mtc-sestamibi scintimammography : effect of lesion site, size and histopathological characteristics. Journal of the Egyptian National Cancer Institute. 2000. Vol. 12, no. 3, pp.183-189.
https://search.emarefa.net/detail/BIM-69486
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 18-189
رقم السجل
BIM-69486
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر