New antimicrobial anthraquinone 6, 61-bis (1, 5, 7- trihydroxy-3 hydroxymethylanthraquinone)‎ isolated from Streptomyces sp. isolate ERI-26

الملخص EN

The present report is about Streptomyces sp.

isolate ERI-26 isolated from the soil sample of Nilgiri forest, Western Ghats.

The methanol extract of ERI-26 showed good antimicrobial activity against tested microbes.

The antimicrobial novel anthraquinones were purified by bioactivity-guided fractionation using a silica gel column and preparative HPLC.

The compound was characterized and identified by UV, IR, NMR and MASS spectral data.

The compound named as 6,61-bis (1,5,7-trihydroxy-3-hydroxymethylanthraquinone), showed significant antimicrobial activities against tested microbes.

The isolated compound inhibited the tested bacterial growth, Staphylococcus aureus at 62.5 lg/ml, Staphylococcus epidermidis at 15.62 lg/m, Bacillus subtilis at 62.5 lg/ml, fungi; Trichophyton mentagrophytes at 15.62 lg/m Trichophyton simii at 15.62 lg/ml, Aspergillus niger at.

7.81 lg/ml, Aspergiller flavus at 3.90 lg/ml, Trichophyton rubrum 296 at 62.5 lg/ml, T.

rubrum 57/01 at 7.81 lg/ml, Magnaporthe grisea at 15.62 lg/ml.

and Botrytis cinerea at 3.90 lg/ml.

Isolated anthraquinone compound and its antimicrobial activity were newly reported.

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